Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed

Permanent URI for this communityhttps://hdl.handle.net/20.500.14719/1741

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Start date: 2010End date: 2019Type: search.filters.itemtype.ReviewHas files: NoAuthor: search.filters.author.Konya, DenizAuthor: search.filters.author.Akakin, Akin

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    Locally Aggressive De Novo Spinal Fibromatosis: Case Report and Review of the Literature
    (TURKISH NEUROSURGICAL SOC, 2015) Eksi, Murat Sakir; Turkoz, Huseyin Kemal; Ozcan Eksi, Emel Ece; Akakin, Akin; Toktas, Zafer Orkun; Konya, Deniz; University of California System; University of California San Francisco; Marmara University; Bahcesehir University
    Fibromatosis is a benign lesion, which originates from proliferating fibroblasts. Although fibromatosis is a benign tumor, it is locally aggressive and invasive. Spinal presentation of fibromatosis is very rare, and case reports are the only source of the clinical knowledge. Herein, we describe the oldest patient having spinal fibromatosis with de novo occurrence and aggressive nature. A 68-year-old female patient admitted to our outpatient clinic with low back pain and neurological claudication. On lumbar spine magnetic resonance imaging, she had spinal canal stenosis with a concomitant lesion in the left longissimus muscle. We did our best to resect the tumor, entirely. The pathology result was consistent with spindle cell lesion. The lesion recurred 6 months after the primary surgery. In the second surgery, we did en bloc resection. Pathology and immunohistochemical analysis results were consistent with fibromatosis. After the second surgery, she had adjuvant radiotherapy. There was nothing other than radionecrosis in the operation site, still after 2 years. In conclusion, radiological work-up is usually insufficient to make fibromatosis diagnosis and whole pathological specimen should be carefully evaluated to achieve the accurate diagnosis. Spinal fibromatosis is very rare and its treatment methods have not universally been conceptualized. However, adjuvant therapies are necessary after en bloc resection.
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    Rare Solitary Primary Osseous Lesions of the Spine in Adults, Challenges in CT and MR Imaging Diagnosis With Pathological Correlation
    (JOURNAL NEUROLOGICAL SCIENCES, 2015) Toktas, Zafer Orkun; Yilmaz, Baran; Akakin, Akin; Demir, Mustafa Kemal; Yapicier, Ozlem; Onat, Elif; Urgun, Kamran; Konya, Deniz; Bahcesehir University; Bahcesehir University; Bahcesehir University
    This pictorial essay is a review of the computerized tomography and magnetic resonance imaging of a few solitary primary osseous lesions encountered in the adults. The lesions discussed include giant cell tumor, Langerhans cell histiocytosis, Paget'sdisease, plasmacytoma, fibrous dysplasia and osteoblastoma. Challenges in computerized tomography and magnetic resonance imaging diagnosis of these lesions are mentioned with clinicoradiological differential diagnosis, and include pathological correlation. Although active diagnosis and radiological familiarity of these lesions is crucial for preventing unnecessary examinations or procedures, pathological evaluation is mandatory to establish final diagnosis.