Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed
Permanent URI for this communityhttps://hdl.handle.net/20.500.14719/1741
Browse
8 results
Search Results
Publication Metadata only Microalgae as a key tool in achieving carbon neutrality for bioproduct production(ELSEVIER, 2023) Sadvakasova, Assemgul K.; Kossalbayev, Bekzhan D.; Bauenova, Meruyert O.; Balouch, Huma; Leong, Yoong Kit; Zayadan, Bolatkhan K.; Huang, Zhiyong; Alharby, Hesham F.; Tomo, Tatsuya; Chang, Jo-Shu; Allakhverdiev, Suleyman I.; Al-Farabi Kazakh National University; Satbayev University; Satbayev University; Tunghai University; Tunghai University; Chinese Academy of Sciences; Tianjin Institute of Industrial Biotechnology, CAS; King Abdulaziz University; Tokyo University of Science; National Cheng Kung University; Yuan Ze University; Russian Academy of Sciences; Timiryazev Institute of Plant Physiology; Lomonosov Moscow State University; Bahcesehir UniversityThe upcoming global climate change as a result of anthropogenic action is now increasingly attracting the attention of scientific communities. Over the past three decades, researchers and industries around the world have spent a lot of time and effort developing various carbon capture and storage technologies, which, despite their promise, are still economically complex, with unclear long-term consequences to the environment. As an alternative, biological carbon sequestration is considered an attractive method of atmospheric CO2 fixation with the production of biomass, which, in turn, can be used as a readily renewable feedstock for the production of biofuels and other valuable products. This review focuses on the latest data of microalgae research in terms of key carbon footprint minimization strategies, which include features of the carbon concentrating mechanism (CCM) in microalgae, the main range of biofuels and the possibility of obtaining valuable metabolites based on them, such as bioplastics, biofertilizers, and biologically active compounds.Publication Unknown Synthetic algocyanobacterial consortium as an alternative to chemical fertilizers(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2023) Sadvakasova, Assemgul K.; Bauenova, Meruyert O.; Kossalbayev, Bekzhan D.; Zayadan, Bolatkhan K.; Huang, Zhiyong; Wang, Jingjing; Balouch, Huma; Alharby, Hesham F.; Chang, Jo-Shu; Allakhverdiev, Suleyman I.; Al-Farabi Kazakh National University; Satbayev University; Satbayev University; Chinese Academy of Sciences; Tianjin Institute of Industrial Biotechnology, CAS; King Abdulaziz University; Tunghai University; Tunghai University; National Cheng Kung University; Yuan Ze University; Russian Academy of Sciences; Timiryazev Institute of Plant Physiology; Bahcesehir UniversityThe use of unregulated pesticides and chemical fertilizers can have detrimental effects on biodiversity and human health. This problem is exacerbated by the growing demand for agricultural products. To address these global challenges and promote food and biological security, a new form of agriculture is needed that aligns with the principles of sustainable development and the circular economy. This entails developing the biotechnology market and maximizing the use of renewable and eco-friendly resources, including organic fertilizers and biofertilizers. Phototrophic microorganisms capable of oxygenic photosynthesis and assimilation of molecular nitrogen play a crucial role in soil microbiota, interacting with diverse microflora. This suggests the potential for creating artificial consortia based on them. Microbial consortia offer advantages over individual organisms as they can perform complex functions and adapt to variable conditions, making them a frontier in synthetic biology. Multifunctional consortia overcome the limitations of monocultures and produce biological products with a wide range of enzymatic activities. Biofertilizers based on such consortia present a viable alternative to chemical fertilizers, addressing the issues associated with their usage. The described capabilities of phototrophic and heterotrophic microbial consortia enable effective and environmentally safe restoration and preservation of soil properties, fertility of disturbed lands, and promotion of plant growth. Hence, the utilization of algo-cyanobacterial consortia biomass can serve as a sustainable and practical substitute for chemical fertilizers, pesticides, and growth promoters. Furthermore, employing these bio-based organisms is a significant stride towards enhancing agricultural productivity, which is an essential requirement to meet the escalating food demands of the growing global population. Utilizing domestic and livestock wastewater, as well as CO2 flue gases, for cultivating this consortium not only helps reduce agricultural waste but also enables the creation of a novel bioproduct within a closed production cycle.Publication Unknown Optimising microalgae-derived butanol yield(PERGAMON-ELSEVIER SCIENCE LTD, 2024) Bauenova, Meruyert O.; Sadvakasova, Assemgul K.; Kossalbayev, Bekzhan D.; Yilmaz, Girayhan; Huang, Zhiyong; Wang, Jingjing; Balouch, Huma; Zaletova, Dilnaz E.; Lyaguta, Mariya A.; Alharby, Hesham F.; Allakhverdiev, Suleyman I.; Al-Farabi Kazakh National University; Akhmet Yassawi International Kazakh-Turkish University; Bahcesehir University; Chinese Academy of Sciences; Tianjin Institute of Industrial Biotechnology, CAS; King Abdulaziz University; Timiryazev Institute of Plant Physiology; Russian Academy of SciencesRapid global urbanisation emphasises the necessity to explore sustainable energy resources to fulfill escalating energy demands. Biobutanol emerges as a promising biofuel due to heightened energy density and molecular similarity to petrol. Microalgae, rich in carbohydrates, offer a potential glucose source for biobutanol fermen-tation. The current study shows that varying CO2 concentrations affect carbohydrate content in the biomass of P. kessleri bh-2 and Scenedesmus sp.k-7. The introduction of 1% CO2 significantly improved carbohydrate pro-ductivity, reaching 74.5% for P. kessleri bh-2 and 71.0% for Scenedesmus sp.k-7. Enzymatic hydrolysis was found to be most effective for ABE fermentation, with optimal results obtained at enzyme loads of 8 mg g 1 cellulase and 2 mg g 1 amylase for both strains. When C. acetobutylicum cells were cultivated with pretreated P. kessleri bh-2 biomass, the biobutanol yield amounted to 4.8 gL-1 at a glucose concentration of 5.30 gL-1, demonstrating strain's superior performance compared to Scenedesmus sp.k-7.Publication Unknown Strategies for genetic modification of microalgae to improve the production efficiency of liquid biofuel(PERGAMON-ELSEVIER SCIENCE LTD, 2025) Kossalbayev, Bekzhan D.; Kakimova, Ardak B.; Sadvakasova, Assemgul K.; Bauenova, Meruyert O.; Balouch, Huma; Zaletova, Maria; Ahmad, Fiaz; Kirbayeva, Dariga K.; Ozgul, Sevim; Allakhverdiev, Suleyman I.; Al-Farabi Kazakh National University; Satbayev University; Akhmet Yassawi International Kazakh-Turkish University; Northwestern Polytechnical University; Bahcesehir University; Russian Academy of Sciences; Timiryazev Institute of Plant PhysiologyThe application of genetic engineering in biofuel production has advanced significantly, driven by developments in genetic tools and omics technologies. These advancements have enhanced our understanding of lipid and carbohydrate metabolism, opening new avenues for metabolic engineering to optimize biofuel production. This review explores genetic strategies to improve the lipid content and fatty acid profiles for biodiesel production, as well as innovations in engineering for one-step biobutanol synthesis using cyanobacteria. Strategies for carbohydrate accumulation are also examined, highlighting their role in biofuel production. Additionally, the review evaluates the environmental risks associated with large-scale fourth-generation biofuel production. The findings emphasize the potential of genetic engineering to transform microalgae into highly efficient biofuel platforms capable of producing biodiesel, biobutanol, and other liquid biofuels. By addressing critical challenges and leveraging cutting-edge technologies, this research contributes to the development of sustainable and economically viable biofuel production systems.Publication Metadata only Prospecting the biofuel potential of new microalgae isolates(Elsevier Ltd, 2023) Balouch, Huma; Zayadan, Bolatkhan K.; Sadvakasova, Asemgul K.; Kossalbayev, Bekzhan D.; Bolatkhan, K.; Gencer, Donus; Civelek, Dilek Ozturk; Demïrbag, Zihni; Alharby, Hesham Fasial; Allakhverdiev, Suleyman I.; Balouch, Huma, Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Zayadan, Bolatkhan K., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Sadvakasova, Asemgul K., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Kossalbayev, Bekzhan D., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan, Department of Chemical and Biochemical Engineering, Satbayev University, Almaty, Kazakhstan; Bolatkhan, K., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Gencer, Donus, Department of Property Protection and Security, Trabzon University, Trabzon, Turkey; Civelek, Dilek Ozturk, Department of Biology, Karadeniz Technical University, Trabzon, Turkey; Demïrbag, Zihni, Department of Biology, Karadeniz Technical University, Trabzon, Turkey; Alharby, Hesham Fasial, Department of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia; Allakhverdiev, Suleyman I., Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Moscow, Russian Federation, Faculty of Engineering and Natural Sciences, Bahçeşehir Üniversitesi, Istanbul, TurkeyThe continued search and urgent need for renewable fuel sources have necessitated the exploration of microalgae to identify relevant species for making biofuels. The aim of the study was bioprospecting and screening native microalgae strains from freshwater habitats of the Almaty region, Kazakhstan, to assess the potential for producing biofuel. The studied strains demonstrated simultaneous biomass productivity, lipid productivity, suitable fatty acid composition, and biodiesel properties. The sequence analysis of the ribosomal DNA internal transcribed spacer partial region and ribulose-bisphosphate carboxylase gene (rbcL) led to the identification of five microalgae: Monoraphidium griffithii ZBD-01, Nephrochlamys subsolitaria ZBD-02, Ankistrodesmus falcatus ZBD-03, Parachlorella kessleri ZBD-04, and Desmodesmus pannonicus ZBD-05. P. kessleri had the highest biomass production (1.42 ± 0.08 g L−1 day−1), lipid productivity (29 ± 1.2 g L−1day−1), and C16–C18 fatty acid contents (90%), followed by A. falcatus and M. griffithi. Gas chromatography/mass spectrometry analysis indicated that the dominant fatty acids in these strains were palmitic, stearic, and oleic acids. The calculated biodiesel properties of P. kessleri and A. falcatus based on fatty acid methyl esters (FAME) profiles showed relatively good fuel properties (cetane numbers - 48 and 50, iodine and saponification values - 83.4 and 103.6 g I₂/100 g oil, 260.8 and 199.5 mg KOH g−1), which correlate well with. Our results suggest that P. kessleri and A. falcatus are promising strains for biodiesel production due to their high lipid productivity, fatty acid profile with relatively high content of oleic acid, and suitable biodiesel properties. The isolated native species of microalgae from natural freshwater bodies of the Almaty region present opportunities for further exploitation for the sustainable production of biomass and biodiesel. © 2023 Elsevier B.V., All rights reserved.Publication Metadata only Synthetic algocyanobacterial consortium as an alternative to chemical fertilizers(Academic Press Inc., 2023) Sadvakasova, Asemgul K.; Bauenova, Meruyert O.; Kossalbayev, Bekzhan D.; Zayadan, Bolatkhan K.; Huang, Zhiyong; Wang, Jingjing; Balouch, Huma; Alharby, Hesham Fasial; Chang, Jo-Shu; Allakhverdiev, Suleyman I.; Sadvakasova, Asemgul K., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Bauenova, Meruyert O., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Kossalbayev, Bekzhan D., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan, Department of Chemical and Biochemical Engineering, Satbayev University, Almaty, Kazakhstan; Zayadan, Bolatkhan K., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Huang, Zhiyong, Tianjin Institute of Industrial Biotechnology, Tianjin, China; Wang, Jingjing, Tianjin Institute of Industrial Biotechnology, Tianjin, China; Balouch, Huma, Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Alharby, Hesham Fasial, Department of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia; Chang, Jo-Shu, Department of Chemical and Materials Engineering, Tunghai University, Taichung, Taiwan, Research Center for Smart Sustainable Circular Economy, Tunghai University, Taichung, Taiwan, National Cheng Kung University, Tainan, Taiwan, Department of Chemical Engineering and Materials Science, Yuan Ze University, Taoyuan, Taiwan; Allakhverdiev, Suleyman I., Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Moscow, Russian Federation, Institute of Fundamental Problems of Biology of the Russian Academy of Sciences, Pushchino, Russian Federation, Faculty of Engineering and Natural Sciences, Bahçeşehir Üniversitesi, Istanbul, TurkeyThe use of unregulated pesticides and chemical fertilizers can have detrimental effects on biodiversity and human health. This problem is exacerbated by the growing demand for agricultural products. To address these global challenges and promote food and biological security, a new form of agriculture is needed that aligns with the principles of sustainable development and the circular economy. This entails developing the biotechnology market and maximizing the use of renewable and eco-friendly resources, including organic fertilizers and biofertilizers. Phototrophic microorganisms capable of oxygenic photosynthesis and assimilation of molecular nitrogen play a crucial role in soil microbiota, interacting with diverse microflora. This suggests the potential for creating artificial consortia based on them. Microbial consortia offer advantages over individual organisms as they can perform complex functions and adapt to variable conditions, making them a frontier in synthetic biology. Multifunctional consortia overcome the limitations of monocultures and produce biological products with a wide range of enzymatic activities. Biofertilizers based on such consortia present a viable alternative to chemical fertilizers, addressing the issues associated with their usage. The described capabilities of phototrophic and heterotrophic microbial consortia enable effective and environmentally safe restoration and preservation of soil properties, fertility of disturbed lands, and promotion of plant growth. Hence, the utilization of algo-cyano-bacterial consortia biomass can serve as a sustainable and practical substitute for chemical fertilizers, pesticides, and growth promoters. Furthermore, employing these bio-based organisms is a significant stride towards enhancing agricultural productivity, which is an essential requirement to meet the escalating food demands of the growing global population. Utilizing domestic and livestock wastewater, as well as CO2 flue gases, for cultivating this consortium not only helps reduce agricultural waste but also enables the creation of a novel bioproduct within a closed production cycle. © 2023 Elsevier B.V., All rights reserved.Publication Metadata only Combating Phytopathogens by Integration of Metagenomics and Phototrophic Biotechnologies: Toward Sustainable Agricultural Practices(Taylor and Francis Ltd., 2025) Sadvakasova, Asemgul K.; Kossalbayev, Bekzhan D.; Zaletova, Dilnaz E.; Bauenova, Meruyert O.; Huang, Zhiyong; Zharmukhamedov, Sergei K.; Shabala, Sergey Nikolayevich; Allakhverdiev, Suleyman I.; Sadvakasova, Asemgul K., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Kossalbayev, Bekzhan D., Department of Chemical and Biochemical Engineering, Satbayev University, Almaty, Kazakhstan, Ecology Research Institute, Khoja Akhmet Yassawi International Kazakh-Turkish University, Turkistan, Kazakhstan; Zaletova, Dilnaz E., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Bauenova, Meruyert O., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Huang, Zhiyong, Tianjin Institute of Industrial Biotechnology, Tianjin, China; Zharmukhamedov, Sergei K., Institute of Fundamental Problems of Biology of the Russian Academy of Sciences, Pushchino, Russian Federation; Shabala, Sergey Nikolayevich, School of Biological Sciences, The University of Western Australia, Perth, Australia; Allakhverdiev, Suleyman I., Institute of Fundamental Problems of Biology of the Russian Academy of Sciences, Pushchino, Russian Federation, Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Moscow, Russian Federation, Faculty of Engineering and Natural Sciences, Bahçeşehir Üniversitesi, Istanbul, TurkeyRising global food demand amid climate change presents unprecedented challenges for modern agriculture. The spread of phytopathogens and the degradation of agroecosystems necessitate the development of innovative plant protection solutions. Traditional chemical pesticides are losing their effectiveness due to the emergence of resistant pathogens and their adverse environmental impacts, thereby intensifying interest in biological control methods. This study examines the integration of metagenomic analysis and phototrophic biotechnology as a promising approach to biocontrol. Metagenomics enables the precise identification of phytopathogens and beneficial microorganisms, laying the groundwork for the development of targeted biopesticides. Phototrophic microorganisms, including microalgae and cyanobacteria, exhibit antimicrobial properties and contribute to the restoration of soil ecosystems. The convergence of these technologies offers opportunities to form adaptive microbial consortia that ensure the long-term sustainability of agroecosystems. The paper discusses key challenges, including data processing complexities, the scalability of technologies, and regulatory barriers, and underscores the need for standardized methodologies and interdisciplinary collaboration. The integration of metagenomics and phototrophic biotechnology represents a promising direction for creating environmentally safe and sustainable agricultural production systems. © 2025 Elsevier B.V., All rights reserved.Publication Metadata only Strategies for genetic modification of microalgae to improve the production efficiency of liquid biofuel(Elsevier Ltd, 2025) Kossalbayev, Bekzhan D.; Kakimova, Ardak B.; Sadvakasova, Asemgul K.; Bauenova, Meruyert O.; Balouch, Huma; Lyaguta, Mariya A.; Ahmad, Fiaz; Kirbayeva, Dariga K.; Özgül, Sevim; Allakhverdiev, Suleyman I.; Kossalbayev, Bekzhan D., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan, Department of Chemical and Biochemical Engineering, Satbayev University, Almaty, Kazakhstan, Ecology Research Institute, Khoja Akhmet Yassawi International Kazakh-Turkish University, Turkistan, Kazakhstan; Kakimova, Ardak B., Department of Chemical and Biochemical Engineering, Satbayev University, Almaty, Kazakhstan, Key Laboratory for Space Bioscience and Biotechnology, Northwestern Polytechnical University, Xi'an, China; Sadvakasova, Asemgul K., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Bauenova, Meruyert O., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Balouch, Huma, Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Lyaguta, Mariya A., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Ahmad, Fiaz, Key Laboratory for Space Bioscience and Biotechnology, Northwestern Polytechnical University, Xi'an, China; Kirbayeva, Dariga K., Faculty of Biology and Biotechnology, Al Farabi Kazakh National University, Almaty, Kazakhstan; Özgül, Sevim, Faculty of Engineering and Natural Sciences, Bahçeşehir Üniversitesi, Istanbul, Turkey; Allakhverdiev, Suleyman I., Faculty of Engineering and Natural Sciences, Bahçeşehir Üniversitesi, Istanbul, Turkey, Controlled Photobiosynthesis Laboratory, Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Moscow, Russian FederationThe application of genetic engineering in biofuel production has advanced significantly, driven by developments in genetic tools and omics technologies. These advancements have enhanced our understanding of lipid and carbohydrate metabolism, opening new avenues for metabolic engineering to optimize biofuel production. This review explores genetic strategies to improve the lipid content and fatty acid profiles for biodiesel production, as well as innovations in engineering for one-step biobutanol synthesis using cyanobacteria. Strategies for carbohydrate accumulation are also examined, highlighting their role in biofuel production. Additionally, the review evaluates the environmental risks associated with large-scale fourth-generation biofuel production. The findings emphasize the potential of genetic engineering to transform microalgae into highly efficient biofuel platforms capable of producing biodiesel, biobutanol, and other liquid biofuels. By addressing critical challenges and leveraging cutting-edge technologies, this research contributes to the development of sustainable and economically viable biofuel production systems. © 2025 Elsevier B.V., All rights reserved.