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  • Publication
    The pros and cons of digital health communication tools in neurosurgery: a systematic review of literature
    (Springer, 2020) Nanah, Abdelrahman; Bayoumi, Ahmed B.; Nanah, Abdelrahman, Faculty of Medicine, Bahçeşehir Üniversitesi, Istanbul, Turkey; Bayoumi, Ahmed B., Faculty of Medicine, Bahçeşehir Üniversitesi, Istanbul, Turkey
    Effective communication is critical in healthcare facilitation. Our aim is to illustrate the impact of digital communication tools in the field of neurosurgery based on the cumulative recently published reports to show an evidence-based review of both benefits and limitations. We performed a systematic review of records published from January 2003 to March 2018. A specific set of keywords such as digital and communication were used on PubMed database to conduct a thorough online search. 13 articles, out of 52, were comprehensively studied after complying with our inclusion and exclusion criteria. Many of the reviewed studies reported several applications of digital health communication tools in neurosurgery including 46% (6/13) in the Emergency Room and 23% (3/13) in the Operating Room. 38.5% (5/13) were applied in teaching hospitals. Reviewed studies were divided into two groups according to their applications (interventional (3/13) and non-interventional (10/13)). In the Emergency Room, digital health tools facilitated timely diagnosis and management, while in the operating room it permitted revolutionary robotic surgery. It showed potential for no-risk learning at academic institutions. While the fruitful impacts were convincing of the digital communication tools’ ability to enhance healthcare in neurosurgery, proper adherence to regulations against data loss and theft, two potential complications of digital tool misuse, must be maintained. Additionally, both time efficiency and the necessity of waiting for better implementation of communication tools proved to be obstacles to consistent digital tool integration. © 2020 Elsevier B.V., All rights reserved.
  • Publication
    Could gas-filled pseudocyst mimick extruded disc herniation?
    (Churchill Livingstone, 2021) Ekşi̇, Murat Şakir; Ece Özcan-Ekşi, Emel; Orhun, Omer; Akkaş, Alper; Harun Yaşar, Ahmet; Zarbizada, Maftun; Canbolat, Cagri; Güdük, Mustafa; Bozkurt, Baran; İmre Usseli, Murat; Ekşi̇, Murat Şakir, Department of Neurosurgery, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, Turkey; Ece Özcan-Ekşi, Emel, Department of Physical Medicine and Rehabilitation, Bahçeşehir Üniversitesi, Istanbul, Turkey; Orhun, Omer, School of Medicine, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, Turkey; Akkaş, Alper, Department of Neurosurgery, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, Turkey; Harun Yaşar, Ahmet, Department of Neurosurgery, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, Turkey; Zarbizada, Maftun, Department of Neurosurgery, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, Turkey; Canbolat, Cagri, Neurosurgery Clinic, Memorial Hizmet Hospital, Istanbul, Turkey; Güdük, Mustafa, Department of Neurosurgery, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, Turkey; Bozkurt, Baran, Department of Neurosurgery, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, Turkey; İmre Usseli, Murat, Department of Neurosurgery, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, Turkey
    There are case reports and small case series in the literature reporting gas-filled pseudocysts (GFP). However, a systematic review presenting overall view of the disease and its management is still lacking. In the present study, we aimed to make a systematic review of GFP cases, and present an exemplary case of ours. Our second aim was to discuss current theories for pathogenesis of GFP. A systematic review of GFP was conducted using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline. Two large-scaled data search engines were used. A total of 53 articles were retrieved from the literature and presented with an exemplary case of ours. Mean age of the historical cohort was 59.47 years. There were 66 male (54.1%) and 56 female (45.9%) patients. The most prevalent clinical presentation was radicular sign/symptom in lower limbs with (29.1%) or without low back pain (LBP) (67%). Gas-filled pseudocyst has most commonly been diagnosed at the lower lumbar spine (L4-L5, 45.3%, L5-S1, 37.7%). Surgery was the treatment of choice in most of the patients (80%). In the whole cohort, 79.1% of the patients had complete recovery. Gas-filled pseudocysts are rarely observed in daily practice. They present mostly in men at the age of 60s. Precise differential diagnosis determination using appropriate imaging would help clinicians treat the patients properly. Gas-filled pseudocysts should be treated similarly to other spinal pathologies causing nerve root compression. © 2022 Elsevier B.V., All rights reserved.
  • Publication
    Effects of high intensity interval training and sprint interval training in patients with asthma: a systematic review
    (Taylor and Francis Ltd., 2022) Ertürk, Gamze; Günday, Çiçek; Evrendilek, Halenur; Sağır, Kübra; Aslan, Gökşen Kuran; Ertürk, Gamze, Institute of Graduate Studies, Istanbul University-Cerrahpasa, Istanbul, Turkey, Department of Physiotherapy and Rehabilitation, T.C. Istanbul Kültür Üniversitesi, Istanbul, Turkey; Günday, Çiçek, Institute of Graduate Studies, Istanbul University-Cerrahpasa, Istanbul, Turkey, Department of Physiotherapy and Rehabilitation, Bahçeşehir Üniversitesi, Istanbul, Turkey; Evrendilek, Halenur, Institute of Graduate Studies, Istanbul University-Cerrahpasa, Istanbul, Turkey, Department of Physiotherapy and Rehabilitation, T.C. Istanbul Kültür Üniversitesi, Istanbul, Turkey; Sağır, Kübra, Institute of Graduate Studies, Istanbul University-Cerrahpasa, Istanbul, Turkey, Department of Physiotherapy and Rehabilitation, İstinye Üniversitesi, Istanbul, Turkey; Aslan, Gökşen Kuran, Department of Physiotherapy and Rehabilitation, Istanbul University-Cerrahpasa, Istanbul, Turkey
    Objective: The aim of this study is to review the effects of high-intensity interval training (HIIT)/sprint interval training (SIT) on asthma symptoms, cardiorespiratory functions, and other variables among asthmatic patients. Data sources: Randomized controlled trials published between January 2000 and January 2021 were searched in PubMed/MEDLINE, Web of Science, and Cochrane Library databases. Study selections: Following pre-specified inclusion criteria, this review included 7 randomized controlled studies that compare HIIT/SIT as an intervention with any other intervention and/or control group. Results: Of the included studies only four reported the chronic phase effects of the HIIT/SIT protocols. HIIT and SIT protocols applied in studies differ. HIIT improved forced expiratory volume in 1 s (FEV1) in the acute phase and maximal oxygen consumption (VO2max) in the chronic phase in the asthmatic patients (p < 0.05). Conclusion: To our knowledge, our systematic review is the first study evaluating the effects of HIIT/SIT protocols on asthma patients. HIIT/SIT protocols have beneficial effects on asthma patients. In order to better understand the results of these training procedures, studies that will be designed with high methodology are needed. © 2022 Elsevier B.V., All rights reserved.
  • Publication
    Is the third trochanter of the femur a developmental anomaly, a functional marker, or an evolutionary adaptation?
    (Taylor and Francis Ltd., 2023) Ogut, E.; Ogut, E., Department of Anatomy, Bahçeşehir Üniversitesi, Istanbul, Turkey
    The third trochanter (TT) is a proximal femoral accessory tubercle at the upper border of the gluteal tuberosity that is unusually encountered on the posterior aspect. However, detailed knowledge about the TT remains limited. For this reason, TT was investigated in all its aspects. To give an overview about the TT, a review was conducted in databases until November 2021. Out of 4981 articles, only 53 articles could be included, most of which were studies conducted on dry femurs. The TT can be a result of the developmental process of gluteus maximus due to posture and bipedal locomotor activity. Another explanation of the formation of TT is the inactivation, deficiency, or mutation of specific genes that cause alterations in the proximal femoral end. The current review leads to the assumption that TT, considered for all mammalians, can be an evolutionary adaptation and may be a result of altered muscle activity, increased mechanical force, and reduced stress on the femoral shaft. Therefore, TT should be used in genomic studies related to the evolution of mammalians. An improvement in study design, the scale of the study, methodology, and the selection of mammalian species may permit more comprehensive analysis and reduce study heterogeneity. © 2023 Elsevier B.V., All rights reserved.
  • Publication
    Investigation of Effects of Preoperative Readiness on Symptom Management in Patients with Intestinal Stoma: A Systematic Review and Meta-Analysis Study
    (Asian Pacific Organization for Cancer Prevention, 2023) Korkmaz, Evin; Eti Aslan, Fatma; Korkmaz, Evin, Northern Campus, Bahçeşehir Üniversitesi, Istanbul, Turkey; Eti Aslan, Fatma, Northern Campus, Bahçeşehir Üniversitesi, Istanbul, Turkey
    Objective: This study aims to examine the effect of preoperative readiness on postoperative symptom management in patients with intestinal stoma through systematic review and meta-analysis. Methods: Intestinal stoma, complications and other related terms were searched regardless of the language of publication in the publications published in the databases until December 29, 2021. Result: As a result, 30 studies were found. Two independent reviewers reviewed the studies, and the methodological quality of the included studies was assessed using the Health Evidence™ Quality Assessment Tool. The Comprehensive Meta-Analysis 3 was used to analyze the data. Publication bias, funnel plot, and the effect size were calculated using Cohen’s kappa. Preparation for intestinal stoma surgery consisted of two main themes, and postoperative complications/problems consisted of nine sub-themes. The meta-analysis results showed that preoperative readiness had a moderate effect size on postoperative complications (d=0.498, d=0.457). Conclusion: It was thus concluded that preoperative practices were significant and effective in postoperative symptom management. © 2023 Elsevier B.V., All rights reserved.
  • Publication
    A Systematic Review of Cavernous Sinus Chondromas and an Illustrative Case Treated With Subtotal Resection Followed by Gamma Knife Radiosurgery
    (Elsevier Inc., 2023) Demir, Mustafa Kemal; Kurtkaya-Yapicier, Özlem Sahan; Ertem, Onder; Paker, Berkay; Zorlu, Emre; Kilic, Turker D.; Demir, Mustafa Kemal, Department of Radiology, Medical Park Hospital, Bursa, Turkey; Kurtkaya-Yapicier, Özlem Sahan, Department of Pathology, Bahçeşehir Üniversitesi, Istanbul, Turkey; Ertem, Onder, Department of Neurosurgery, Bahçeşehir Üniversitesi, Istanbul, Turkey; Paker, Berkay, Department of Neurosurgery, Bahçeşehir Üniversitesi, Istanbul, Turkey; Zorlu, Emre, Department of Neurosurgery, Bahçeşehir Üniversitesi, Istanbul, Turkey; Kilic, Turker D., Department of Neurosurgery, Bahçeşehir Üniversitesi, Istanbul, Turkey
    [No abstract available]
  • Publication
    The Guillain-Mollaret triangle: a key player in motor coordination and control with implications for neurological disorders
    (Springer Science and Business Media Deutschland GmbH, 2023) Ogut, E.; Armagan, Kutay; Tufekci, Doruktan; Ogut, E., Department of Anatomy, Bahçeşehir Üniversitesi, Istanbul, Turkey; Armagan, Kutay, Medical Faculty Student, Bahçeşehir Üniversitesi, Istanbul, Turkey; Tufekci, Doruktan, Medical Faculty Student, Bahçeşehir Üniversitesi, Istanbul, Turkey
    The dentato-rubro-olivary pathway, also known as the Guillain-Mollaret triangle (GMT) or myoclonic triangle, consists of the dentate nucleus, the red nucleus, and the inferior olivary nucleus (ION). GMT is important for motor coordination and control, and abnormalities in this network can lead to various neurological disorders. The present study followed a systematic approach in conducting a review on GMT studies. The inclusion criteria were limited to human subjects with primary objectives of characterizing and evaluating GMT syndromes, and the methodology used was not a determining factor for eligibility. The search strategy used MeSH terms and keywords relevant to the study’s objective in various databases until August 2022. A total of 76 studies were included in the review after assessing 527 articles for eligibility based on the final inclusion criteria. Most of the studies evaluated the GMT in human subjects, with the majority utilizing magnetic resonance imaging (MRI), diffusion tensor imaging (DTI), or combination of them. The review found that Hypertrophic olivary degeneration (HOD), a common consequence of GMT damage, has diverse underlying causes, including stroke, brainstem cavernous malformations, and structural impairments. Palatal tremor, ocular myoclonus, ataxia, nystagmus, and vertigo were frequently reported symptoms associated with HOD. This systematic review provides comprehensive insights into the association between GMT and various neurological syndromes, shedding light on the diagnostic, etiological, and prognostic aspects of GMT dysfunction. Understanding the role of the GMT and its implications in movement disorders could pave the way for improved treatment options and better management of neurological conditions related to this critical brainstem pathway. © 2023 Elsevier B.V., All rights reserved.
  • Publication
    Machine learning based algorithms for virtual early detection and screening of neurodegenerative and neurocognitive disorders: a systematic-review
    (Frontiers Media SA, 2024) Yousefi, Milad; Akhbari, Matin; Mohamadi, Zhina; Karami, Shaghayegh; Dasoomi, Hediyeh; Atabi, Alireza; Sarkeshikian, Seyed Amirali; Abdoullahi Dehaki, Mahdi; Bayati, Hesam; Mashayekhi, Negin; Yousefi, Milad, Shahid Beheshti University, Tehran, Iran; Akhbari, Matin, Faculty of Medicine, İstanbul Yeni Yüzyıl Üniversitesi, Zeytinburnu, Turkey; Mohamadi, Zhina, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran; Karami, Shaghayegh, School of Medicine, Tehran, Iran; Dasoomi, Hediyeh, Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Atabi, Alireza, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Sarkeshikian, Seyed Amirali, SBUMS School of Medicine, Tehran, Iran; Abdoullahi Dehaki, Mahdi, Master’s of AI Engineering, Islamic Azad University, Tehran, Iran; Bayati, Hesam, Department of Radiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Mashayekhi, Negin, Department of Neuroscience, Bahçeşehir Üniversitesi, Istanbul, Turkey
    Background and aim: Neurodegenerative disorders (e.g., Alzheimer’s, Parkinson’s) lead to neuronal loss, neurocognitive disorders (e.g., delirium, dementia) show cognitive decline. Early detection is crucial for effective management. Machine learning aids in more precise disease identification, potentially transforming healthcare. This comprehensive systematic review discusses how machine learning (ML), can enhance early detection of these disorders, surpassing traditional diagnostics’ constraints. Methods: In this review, databases were examined up to August 15th, 2023, for ML data on neurodegenerative and neurocognitive diseases using PubMed, Scopus, Google Scholar, and Web of Science. Two investigators used the RAYYAN intelligence tool for systematic reviews to conduct the screening. Six blinded reviewers reviewed titles/abstracts. Cochrane risk of bias tool was used for quality assessment. Results: Our search found 7,069 research studies, of which 1,365 items were duplicates and thus removed. Four thousand three hundred and thirty four studies were screened, and 108 articles met the criteria for inclusion after preprocessing. Twelve ML algorithms were observed for dementia, showing promise in early detection. Eighteen ML algorithms were identified for Parkinson’s, each effective in detection and diagnosis. Studies emphasized that ML algorithms are necessary for Alzheimer’s to be successful. Fourteen ML algorithms were discovered for mild cognitive impairment, with LASSO logistic regression being the only one with unpromising results. Conclusion: This review emphasizes the pressing necessity of integrating verified digital health resources into conventional medical practice. This integration may signify a new era in the early detection of neurodegenerative and neurocognitive illnesses, potentially changing the course of these conditions for millions globally. This study showcases specific and statistically significant findings to illustrate the progress in the area and the prospective influence of these advancements on the global management of neurocognitive and neurodegenerative illnesses. © 2024 Elsevier B.V., All rights reserved.
  • Publication
    Clinical management of uterine contraction abnormalities, an evidence-based intrapartum care algorithm
    (John Wiley and Sons Inc, 2024) Gülümser, Çaǧri; Yassa, Murat; Oliveira-Ciabati, Lívia; de Oliveira, Lariza Laura; Souza, Renato T.; Browne, Joyce Linda; Rijken, Marcus J.; Fawcus, Susan R.; Hofmeyr, George Justus; Liabsuetrakul, Tippawan; Gülümser, Çaǧri, Department of Obstetrics and Gynecology, Yüksek İhtisas Üniversitesi, Ankara, Turkey; Yassa, Murat, Department of Obstetrics and Gynecology, Bahçeşehir Üniversitesi, Istanbul, Turkey; Oliveira-Ciabati, Lívia,; de Oliveira, Lariza Laura,; Souza, Renato T.,; Browne, Joyce Linda,; Rijken, Marcus J.,; Fawcus, Susan R.,; Hofmeyr, George Justus,; Liabsuetrakul, Tippawan,
    Aim: To develop algorithms as decision support tools for identifying, managing and monitoring abnormal uterine activity during labour. Population: Women with singleton, term (37–42 weeks) pregnancies in active labour at admission. Setting: Institutional birth settings in low- and middle-income countries (the algorithm may be applicable to any health facility). Search strategy: PubMed was searched up to January 2020 using keywords. We also searched The Cochrane Library, and international guidelines from World Health Organization (WHO), National Institute for Health and Care Excellence (NICE), American College of Obstetricians and Gynecologists (ACOG) and French College of Gynaecologists and Obstetricians (CNGOF). Case scenarios: Algorithms were developed for two case scenarios: uterine hypoactivity and excessive uterine contractions. Key themes in the algorithm are: diagnosis, identification of probable causes, assessment of maternal and fetal condition and labour progress, monitoring and management. Conclusion: The algorithms for uterine hypoactivity and excessive uterine contractions have been developed to facilitate safe and effective management of abnormal uterine activity during labour. Research is needed to assess the views of healthcare professionals and women accessing healthcare to explore the feasibility of implementing these algorithms, and impact on labour outcomes. Tweetable abstract: An evidence-based algorithm to support clinical management of abnormal uterine activity during labour. © 2024 Elsevier B.V., All rights reserved.
  • Publication
    Health information systems with technology acceptance model approach: A systematic review
    (Elsevier Ireland Ltd, 2024) Tetik, Gozde; Türkeli, Serkan; Pinar, Sevcan; Tarim, Mehveş; Tetik, Gozde, Department of Health Management, Marmara Üniversitesi, Istanbul, Turkey, Department of Management, İstanbul Gelişim Üniversitesi, Istanbul, Turkey; Türkeli, Serkan, Department of Health Informatics and Technologies, Marmara Üniversitesi, Istanbul, Turkey; Pinar, Sevcan, Faculty of Education, Bahçeşehir Üniversitesi, Istanbul, Turkey, Faculty of Arts and Social Sciences, Istanbul Galata University, Istanbul, Turkey; Tarim, Mehveş, Department of Health Management, Marmara Üniversitesi, Istanbul, Turkey
    In the rapidly evolving landscape of information technologies, individuals and organizations must adapt to the digital age. Given the diversity in users’ knowledge and experience with technology, their acceptance levels also vary. Over the past 30 years, various theoretical models have been introduced to provide a framework for understanding user acceptance of technology. Among these, the Technology Acceptance Model (TAM) stands out as a key theoretical framework, offering insights into why new technologies are either accepted or rejected. Analyzing user acceptance of technology has thus become a critical area of study. Healthcare organizations aim to assess the perceived efficacy and user-friendliness of a given technology. This will help health organisations design and implement HIS that meet users’ needs and preferences. In this context, how does the TAM clarify the acceptance and use of Health Information Systems (HIS)? To address this inquiry, a comprehensive literature review will be carried out. The systematic review involved 29 studies issued between 2018 and 2023 and searched the databases Pubmed, Scopus, Wos and Ulakbim TR Index. The PRISMA flowchart was used to identify the included studies. According to the results, some variables stand out in the acceptance and utilisation of HIS. Among the users of HIS, it can be said that the results relating to nurses stand out. In particular, there are studies which emphasise that ’gender’ is a crucial factor in explaining the models. Another crucial finding of the current systematic review is the need to train users in the acceptance and use of HIS. © 2024 Elsevier B.V., All rights reserved.