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Publication Metadata only The pros and cons of digital health communication tools in neurosurgery: a systematic review of literature(Springer, 2020) Nanah, Abdelrahman; Bayoumi, Ahmed B.; Nanah, Abdelrahman, Faculty of Medicine, Bahçeşehir Üniversitesi, Istanbul, Turkey; Bayoumi, Ahmed B., Faculty of Medicine, Bahçeşehir Üniversitesi, Istanbul, TurkeyEffective communication is critical in healthcare facilitation. Our aim is to illustrate the impact of digital communication tools in the field of neurosurgery based on the cumulative recently published reports to show an evidence-based review of both benefits and limitations. We performed a systematic review of records published from January 2003 to March 2018. A specific set of keywords such as digital and communication were used on PubMed database to conduct a thorough online search. 13 articles, out of 52, were comprehensively studied after complying with our inclusion and exclusion criteria. Many of the reviewed studies reported several applications of digital health communication tools in neurosurgery including 46% (6/13) in the Emergency Room and 23% (3/13) in the Operating Room. 38.5% (5/13) were applied in teaching hospitals. Reviewed studies were divided into two groups according to their applications (interventional (3/13) and non-interventional (10/13)). In the Emergency Room, digital health tools facilitated timely diagnosis and management, while in the operating room it permitted revolutionary robotic surgery. It showed potential for no-risk learning at academic institutions. While the fruitful impacts were convincing of the digital communication tools’ ability to enhance healthcare in neurosurgery, proper adherence to regulations against data loss and theft, two potential complications of digital tool misuse, must be maintained. Additionally, both time efficiency and the necessity of waiting for better implementation of communication tools proved to be obstacles to consistent digital tool integration. © 2020 Elsevier B.V., All rights reserved.Publication Open Access Anemia and iron metabolism in COVID-19: a systematic review and meta-analysis(Springer [email protected], 2020) Taneri, Petek Eylul; Gómez-Ochoa, Sergio Alejandro; Llanaj, Erand; Raguindin, Peter Francis; Rojas, Lyda Z.; Roa-Díaz, Zayne Milena; Salvador, Dante Jr; Groothof, Dion; Minder, Beatrice; Kopp-Heim, Doris; Taneri, Petek Eylul, Public Health Department, Bahçeşehir Üniversitesi, Istanbul, Turkey; Gómez-Ochoa, Sergio Alejandro, Public Health and Epidemiological Studies Group, Cardiovascular Foundation of Colombia, Santander, Colombia; Llanaj, Erand, School of Health Sciences, Debreceni Egyetem, Debrecen, Hungary, Public Health Research Institute, Debreceni Egyetem, Debrecen, Hungary; Raguindin, Peter Francis, Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland, Institute of Child Health and Human Development, National Institutes of Health, University of the Philippines Manila, Manila, Philippines, Swiss Paraplegic Centre, Nottwil, Switzerland; Rojas, Lyda Z., Public Health and Epidemiological Studies Group, Cardiovascular Foundation of Colombia, Santander, Colombia, Research Group and Development of Nursing Knowledge (GIDCEN-FCV), Cardiovascular Foundation of Colombia, Santander, Colombia; Roa-Díaz, Zayne Milena, Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland; Salvador, Dante Jr, Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland; Groothof, Dion, Department of Internal Medicine, Universitair Medisch Centrum Groningen, Groningen, Netherlands; Minder, Beatrice, Public Health & Primary Care Library, University of Bern, Bern, Switzerland; Kopp-Heim, Doris, Public Health & Primary Care Library, University of Bern, Bern, SwitzerlandIron metabolism and anemia may play an important role in multiple organ dysfunction syndrome in Coronavirus disease 2019 (COVID-19). We conducted a systematic review and meta-analysis to evaluate biomarkers of anemia and iron metabolism (hemoglobin, ferritin, transferrin, soluble transferrin receptor, hepcidin, haptoglobin, unsaturated iron-binding capacity, erythropoietin, free erythrocyte protoporphyrine, and erythrocyte indices) in patients diagnosed with COVID-19, and explored their prognostic value. Six bibliographic databases were searched up to August 3rd 2020. We included 189 unique studies, with data from 57,563 COVID-19 patients. Pooled mean hemoglobin and ferritin levels in COVID-19 patients across all ages were 129.7 g/L (95% Confidence Interval (CI), 128.51, 130.88) and 777.33 ng/mL (95% CI, 701.33, 852.77), respectively. Hemoglobin levels were lower with older age, higher percentage of subjects with diabetes, hypertension and overall comorbidities, and admitted to intensive care. Ferritin level increased with older age, increasing proportion of hypertensive study participants, and increasing proportion of mortality. Compared to moderate cases, severe COVID-19 cases had lower hemoglobin [weighted mean difference (WMD), − 4.08 g/L (95% CI − 5.12, − 3.05)] and red blood cell count [WMD, − 0.16 × 1012 /L (95% CI − 0.31, − 0.014)], and higher ferritin [WMD, − 473.25 ng/mL (95% CI 382.52, 563.98)] and red cell distribution width [WMD, 1.82% (95% CI 0.10, 3.55)]. A significant difference in mean ferritin levels of 606.37 ng/mL (95% CI 461.86, 750.88) was found between survivors and non-survivors, but not in hemoglobin levels. Future studies should explore the impact of iron metabolism and anemia in the pathophysiology, prognosis, and treatment of COVID-19. © 2020 Elsevier B.V., All rights reserved.Publication Metadata only Glucose management for exercise using continuous glucose monitoring (CGM) and intermittently scanned CGM (isCGM) systems in type 1 diabetes: position statement of the European Association for the Study of Diabetes (EASD) and of the International Society for Pediatric and Adolescent Diabetes (ISPAD) endorsed by JDRF and supported by the American Diabetes Association (ADA)(Springer Science and Business Media Deutschland GmbH, 2020) Moser, Othmar; Riddell, Michael C.; Eckstein, Max Lennart; Adolfsson, Peter; Rabasa-Lhoret, R.; van den Boom, Louisa; Gillard, Pieter G.T.; Nørgaard, Kirsten; Oliver, Nick S.; Zaharieva, Dessi P.; Moser, Othmar, Department of Internal Medicine, Medizinische Universität Graz, Graz, Austria, Department of Sport Science, Universität Bayreuth, Bayreuth, Germany; Riddell, Michael C., School of Kinesiology and Health Science, York University, Toronto, Canada; Eckstein, Max Lennart, Department of Internal Medicine, Medizinische Universität Graz, Graz, Austria; Adolfsson, Peter, Department of Pediatrics, Hospital of Halland, Kungsbacka, Sweden, Institutionen för Kliniska Vetenskaper, Gothenburg, Sweden; Rabasa-Lhoret, R., Institut de Recherches Cliniques de Montréal, Montreal, Canada, Centre Hospitalier de L'Université de Montréal, Montreal, Canada, Department of Nutrition, University of Montreal, Montreal, Canada, Montreal Diabetes Research Centre, Montreal, Canada; van den Boom, Louisa, Division of Pediatric Diabetology, DRK Children's Hospital, Siegen, Germany; Gillard, Pieter G.T., KU Leuven– University Hospital Leuven, Leuven, Belgium; Nørgaard, Kirsten, Københavns Universitet, Copenhagen, Denmark; Oliver, Nick S., Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom; Zaharieva, Dessi P., Department of Endocrinology and Diabetes, Stanford University School of Medicine, Stanford, United StatesPhysical exercise is an important component in the management of type 1 diabetes across the lifespan. Yet, acute exercise increases the risk of dysglycaemia, and the direction of glycaemic excursions depends, to some extent, on the intensity and duration of the type of exercise. Understandably, fear of hypoglycaemia is one of the strongest barriers to incorporating exercise into daily life. Risk of hypoglycaemia during and after exercise can be lowered when insulin-dose adjustments are made and/or additional carbohydrates are consumed. Glycaemic management during exercise has been made easier with continuous glucose monitoring (CGM) and intermittently scanned continuous glucose monitoring (isCGM) systems, however, because of the complexity of CGM and isCGM systems, both individuals with type 1 diabetes and their healthcare professionals may struggle with the interpretation of given information to maximise the technological potential for effective use around exercise (i.e. before, during and after). This position statement highlights the recent advancements in CGM and isCGM technology, with a focus on the evidence base for their efficacy to sense glucose around exercise and adaptations in the use of these emerging tools, and updates the guidance for exercise in adults, children and adolescents with type 1 diabetes. [Figure not available: see fulltext.] © 2020 Elsevier B.V., All rights reserved.Publication Open Access The effect of comorbidity on mortality in elderly patients undergoing emergency abdominal surgery: A systematic review and metaanalysis(Turkiye Klinikleri, 2021) Cinar, F.; Parlak, Göknur; Eti Aslan, Fatma; Cinar, F., Department of Management, İstanbul Sabahattin Zaim University, Kucukcekmece, Turkey; Parlak, Göknur, Department of Nursing, Bahçeşehir Üniversitesi, Istanbul, Turkey; Eti Aslan, Fatma, Department of Nursing, Bahçeşehir Üniversitesi, Istanbul, TurkeyBackground/aim: With the increase in the elderly population, the elderly proportion needing emergency surgery is also increasing. Despite medical advances in surgery and anesthesia, negative postoperative outcomes and high mortality rates are still present in elderly patients undergoing emergency surgery. Comorbidities are described as the main determining factors in poor outcomes. In this metaanalysis, it was aimed to investigate the effect of comorbidity on mortality in elderly patients undergoing emergency abdominal surgery. Materials and methods: The studies published between 2010-2019 were scanned from databases of Google Scholar, Cinahl, Pub Med, Medline and Web of Science. Quality criteria proposed by Polit and Beck were used in the evaluation of the included studies. Interrater agreement was calculated by using the Kappa statistic, effect size by using the odds ratio, and heterogeneity among studies by using the Cochran’s Q statistics. Kendall’s Tau-b coefficient and funnel plot were used to determine publication bias. Results: A total of 9 studies were included in the research. There was a total of 1330 cases in the studies. The total mortality rate was 21% (n = 279), the total rate of having a comorbid factor was 83.6% (n = 1112), and the rate of having a comorbid factor in mortality was 89.2% (n = 249). According to the fixed effects model, the total effect size of comorbid factors on causing mortality was not statistically significant with a value of 1.296 (C.I, 0.84-1.97, P > 0.05). Conclusion: Our study revealed that comorbidity had no significant effect on causing mortality in geriatric patients undergoing emergency abdominal surgery. There are controversial results in the literature, and in order to reach more precise results, studies involving wider groups of patients and further studies examining the specific effect of certain comorbid conditions are needed. © 2021 Elsevier B.V., All rights reserved.Publication Open Access Application of machine learning to improve dairy farm management: A systematic literature review(Elsevier B.V., 2021) Slob, Naftali; Catal, Cagatay; Kassahun, Ayalew; Slob, Naftali, Information Technology Group, Wageningen University & Research, Wageningen, Netherlands; Catal, Cagatay, Department of Computer Engineering, Bahçeşehir Üniversitesi, Istanbul, Turkey; Kassahun, Ayalew, Information Technology Group, Wageningen University & Research, Wageningen, NetherlandsIn recent years, several researchers and practitioners applied machine learning algorithms in the dairy farm context and discussed several solutions to predict various variables of interest, most of which were related to incipient diseases. The objective of this article is to identify, assess, and synthesize the papers that discuss the application of machine learning in the dairy farm management context. Using a systematic literature review (SLR) protocol, we retrieved 427 papers, of which 38 papers were determined as primary studies and thus were analysed in detail. More than half of the papers (55 %) addressed disease detection. The other two categories of problems addressed were milk production and milk quality. Seventy-one independent variables were identified and grouped into seven categories. The two prominent categories that were used in more than half of the papers were milking parameters and milk properties. The other categories of independent variables were milk content, pregnancy/calving information, cow characteristics, lactation, and farm characteristics. Twenty-three algorithms were identified, which we grouped into four categories. Decision tree-based algorithms are by far the most used followed by artificial neural network-based algorithms. Regression-based algorithms and other algorithms that do not belong to the previous categories were used in 13 papers. Twenty-three evaluation parameters were identified of which 7 were used 3 or more times. The three evaluation parameters that were used by more than half of the papers are sensitivity, specificity, RMSE. The challenges most encountered were feature selection and unbalanced data and together with problem size, overfitting/estimating, and parameter tuning account for three-quarters of the challenges identified. To the best of our knowledge, this is the first SLR study on the use of machine learning to improve dairy farm management, and to this end, this study will be valuable not only for researchers but also practitioners in dairy farms. © 2021 Elsevier B.V., All rights reserved.Publication Open Access Oat intake and risk of type 2 diabetes, cardiovascular disease and all-cause mortality: A systematic review and meta-analysis(MDPI, 2021) Wehrli, Faina; Taneri, Petek Eylul; Bano, Arjola; Bally, Lia; Blekkenhorst, Lauren C.; Bussler, Weston W.; Metzger, Brandon T.; Minder, Beatrice; Glisic, Marija; Muka, Taulant; Wehrli, Faina, Institute of Social and Preventive Medicine, Bern, Switzerland; Taneri, Petek Eylul, Institute of Social and Preventive Medicine, Bern, Switzerland, Department Istanbul, Bahçeşehir Üniversitesi, Istanbul, Turkey; Bano, Arjola, Institute of Social and Preventive Medicine, Bern, Switzerland, University Hospital Bern, Bern, Switzerland; Bally, Lia, Department of Diabetes, University of Bern, Bern, Switzerland; Blekkenhorst, Lauren C., School of Medical and Health Sciences, Edith Cowan University, Perth, Australia, The University of Western Australia, Perth, Australia; Bussler, Weston W., Standard Process Nutrition Innovation Center, Kannapolis, United States; Metzger, Brandon T., Standard Process Nutrition Innovation Center, Kannapolis, United States; Minder, Beatrice, Public Health & Primary Care Library, University of Bern, Bern, Switzerland; Glisic, Marija, Institute of Social and Preventive Medicine, Bern, Switzerland; Muka, Taulant, Institute of Social and Preventive Medicine, Bern, SwitzerlandCardiovascular disease (CVD) and type 2 diabetes (T2D) remain the top disease and mortality burdens worldwide. Oats have been shown to benefit cardiovascular health and improve insulin resistance. However, the evidence linking oat consumption with CVD, T2D and all-cause mortality remains inconclusive. We conducted a comprehensive systematic review and meta-analysis of prospective cohort studies to evaluate the associations between oat consumption and risks of T2D, CVD and all-cause mortality in the general population. Five electronic databases were searched until September, 2020. Study specific relative risks (RR) were meta-analyzed using random effect models. Of 4686 relevant references, we included 9 articles, based on 8 unique studies and 471,157 participants. Comparing oat consumers versus non-consumers, RRs were 0.86 (95% CI 0.72– 1.03) for T2D incidence and 0.73 (95% CI 0.5–1.07) for combined CVD incidence. Comparing participants with highest versus lowest oat intake, RRs were 0.78 (95% CI 0.74–0.82) for T2D incidence, 0.81 (95% CI 0.61–1.08) for CHD incidence and 0.79 (95% CI 0.59–1.07) for stroke. For all-cause mortality one study based on three cohorts found RR for men and women were 0.76 (95% CI 0.69–0.85) and 0.78 (95% CI 0.70–0.87), respectively. Most studies (n = 6) were of fair to good quality. This meta-analysis suggests that consumption of oat could reduce the risk for T2D and all-cause mortality, while no significant association was found for CVD. Future studies should address a lack of standardized methods in assessing overall oat intake and type of oat products, and investigate a dose-dependent response of oat products on cardiometabolic outcomes in order to introduce oat as preventive and treatment options for the public. © 2021 Elsevier B.V., All rights reserved.Publication Open Access Adherence to Anti-hypertensive Treatment in Geriatric Patients: A Systematic Review and Meta-analysis, Geriatrik Hastaların Anti-hipertansif Tedaviye Uyumu: Sistematik Derleme ve Metaanaliz(Ortadog u Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S., 2021) Özdemir Aslan, Emine Özdemir; Cinar, F.; Eti Aslan, Fatma; Özdemir Aslan, Emine Özdemir, Department of Nursing, Bahçeşehir Üniversitesi, Istanbul, Turkey; Cinar, F., Department of Health Management, Sebahattin Zaim University Faculty of Health Sciences, Istanbul, Turkey; Eti Aslan, Fatma, Department of Nursing, Bahçeşehir Üniversitesi, Istanbul, TurkeyObjective: This study was planned for the systematic review and meta-analysis of the studies evaluating adherence to antihypertensive treatment in geriatric patients. Material and Methods: Google Scholar, Web of Science, PubMed, CINAHL, MEDLINE and Scopus databases were searched using the keywords Geriatric, Geriatric patients, Elderly, Elderly patients, Hypertension, Anti-hypertensive agents, Drug compliance. A total of 13 studies were included in the meta-analysis. The included studies were evaluated with the quality evaluation criteria proposed by Polit and Beck. The agreement between the researchers was measured by the kappa test for agreement. The odds ratio was used for effect sizes, Cochran's Q test was used for heterogeneity, the funnel plot and Kendall's tau coefficient were used for publication bias. Results: Age, gender, educational status, income level, place of residence and presence of comorbid diseases that affect adherence to anti-hypertensive treatment in geriatric patients were examined. The fact that age and presence of comorbid diseases decreased adherence to anti-hypertensive treatment (OR <1) while being a resident of the city, high educational status, and income level increased adherence to anti-hypertensive treatment (OR >1) in geriatric patients was confirmed by the meta-analysis. Conclusion: The factors affecting adherence to anti-hypertensive treatment in geriatric patients were found to be similar to the literature. In contrast to the literature, it was found that gender did not affect adherence to anti-hypertensive treatment in any way. This difference was thought to be due to the lack of homogeneity in the samples of the studies. © 2022 Elsevier B.V., All rights reserved.Publication Metadata only Elderly patients and falls: a systematic review and meta-analysis(Springer Science and Business Media Deutschland GmbH, 2021) Hacidursunoğlu Erbaş, Dilay; Cinar, F.; Eti Aslan, Fatma; Hacidursunoğlu Erbaş, Dilay, Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital, Istanbul, Turkey; Cinar, F., Faculty of Health Scıences/Department of Health Management, İstanbul Sabahattin Zaim University, Kucukcekmece, Turkey; Eti Aslan, Fatma, Faculty of Health Sciences, Bahçeşehir Üniversitesi, Istanbul, TurkeyObjective: The predetermination of the risk for falls in elderly patients, who will have or had a surgery, enables one to carry out the protective/preventive interventions on this matter. The aim of this review was to provide an up-to-date meta-analysis with regard to falls in elderly surgical patients. Materials and methods: The studies, which were carried out on elderly patients between January 2009 and November 2019 and which investigated the risk factors for falls in elderly surgical patients, were screened on the databases of Google Scholar, Pubmed, Ovid, Cinahl through various combinations of keywords, such as geriatrics, aged, surgery, accidental falls in English or Turkish, to determine the risk factors for the falls in elderly surgical patients. Results: Meeting the study inclusion criteria, 18 studies were analyzed. Of these studies, three were retrospective, seven descriptive, two case–control, four cross-sectional, and two prospective. The kappa value of the general rate of agreement was found as 0.84. No publication bias found in the studies included (Kendall’s tau b = 0.31, p = 0.07) in the meta-analysis based on the values calculated. Conclusion: In this meta-analysis, it was determined that the falls in elderly surgical patients were quite a prevalent public health problem, that the presence of chronic diseases and previous history of falls constituted an extremely high risk for the falls in elderly patients, and that the age or the presence of a gait-inhibiting condition did not constitute any risk for the falls in elderly patients. © 2022 Elsevier B.V., All rights reserved.Publication Open Access COVID-19-associated mucormycosis: Case report and systematic review(Elsevier Inc., 2021) Dilek, Ahmet; Özaras, Reŝat; Özkaya, Şevket; Sünbül, Mustafa; Sen, Elif Itir; Leblebicioglu, Hakan; Dilek, Ahmet, Intensive Care Unit, Samsun Medicalpark Hospital, Samsun, Turkey, İstinye Üniversitesi, Istanbul, Turkey; Özaras, Reŝat, Department of Infectious Diseases, Medilife Health Group, Istanbul, Turkey; Özkaya, Şevket, Department of Pulmonology, Samsun Medicalpark Hospital, Samsun, Turkey, Department of Pulmonology, Bahçeşehir Üniversitesi, Istanbul, Turkey; Sünbül, Mustafa, Department of Infectious Diseases, Samsun Liv Hospital, Samsun, Turkey; Sen, Elif Itir, Bahçeşehir Üniversitesi, Istanbul, Turkey; Leblebicioglu, Hakan, Department of Infectious Diseases, Samsun Medicalpark Hospital, Samsun, TurkeyBackground: Increasing number of patients with COVID-19-associated mucormycosis have been reported, especially from India recently. We have described a patient with COVID-19-associated mucormycosis and, searched and analyzed current medical literature to delineate the characteristics of COVID-19-associated mucormycosis. Method: We reported a patient developed mucormycosis during post-COVID period. We searched literature to describe the incidence, clinical features, and outcomes of COVID-19-associated mucormycosis. Demographic features, risk factors, clinical features, diagnostic methods, treatment and outcome were analyzed. Results: We describe a 54-year-old male, hospitalized due to severe COVID-19 pneumonia. He was given long-term, high doses of systemic steroids. He developed maxillo-fascial mucormycosis and died of sepsis. Our literature search found 30 publications describing 100 patients including present case report. The majority (n = 68) were reported from India. 76% were male. The most commonly seen risk factors were corticosteroid use (90.5%), diabetes (79%), and hypertension (34%). Also, excessive use of broad-spectrum antibiotics were noted in cases. Most frequent involvements were rhino-orbital (50%), followed by rhino-sinusal (17%), and rhino-orbito-cerebral (15%). Death was reported as 33 out of 99 patients (33,3%). Conclusions: Steroid use, diabetes, environmental conditions, excessive use of antibiotics, and hypoxia are main risk factors. Despite medical and surgical treatment, mortality rate is high. A multidisciplinary approach is essential to improve the conditions facilitating the emergence of COVID-19-associated mucormycosis. © 2021 Elsevier B.V., All rights reserved.Publication Metadata only Could gas-filled pseudocyst mimick extruded disc herniation?(Churchill Livingstone, 2021) Ekşi̇, Murat Şakir; Ece Özcan-Ekşi, Emel; Orhun, Omer; Akkaş, Alper; Harun Yaşar, Ahmet; Zarbizada, Maftun; Canbolat, Cagri; Güdük, Mustafa; Bozkurt, Baran; İmre Usseli, Murat; Ekşi̇, Murat Şakir, Department of Neurosurgery, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, Turkey; Ece Özcan-Ekşi, Emel, Department of Physical Medicine and Rehabilitation, Bahçeşehir Üniversitesi, Istanbul, Turkey; Orhun, Omer, School of Medicine, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, Turkey; Akkaş, Alper, Department of Neurosurgery, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, Turkey; Harun Yaşar, Ahmet, Department of Neurosurgery, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, Turkey; Zarbizada, Maftun, Department of Neurosurgery, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, Turkey; Canbolat, Cagri, Neurosurgery Clinic, Memorial Hizmet Hospital, Istanbul, Turkey; Güdük, Mustafa, Department of Neurosurgery, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, Turkey; Bozkurt, Baran, Department of Neurosurgery, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, Turkey; İmre Usseli, Murat, Department of Neurosurgery, Acıbadem Mehmet Ali Aydınlar Üniversitesi, Istanbul, TurkeyThere are case reports and small case series in the literature reporting gas-filled pseudocysts (GFP). However, a systematic review presenting overall view of the disease and its management is still lacking. In the present study, we aimed to make a systematic review of GFP cases, and present an exemplary case of ours. Our second aim was to discuss current theories for pathogenesis of GFP. A systematic review of GFP was conducted using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline. Two large-scaled data search engines were used. A total of 53 articles were retrieved from the literature and presented with an exemplary case of ours. Mean age of the historical cohort was 59.47 years. There were 66 male (54.1%) and 56 female (45.9%) patients. The most prevalent clinical presentation was radicular sign/symptom in lower limbs with (29.1%) or without low back pain (LBP) (67%). Gas-filled pseudocyst has most commonly been diagnosed at the lower lumbar spine (L4-L5, 45.3%, L5-S1, 37.7%). Surgery was the treatment of choice in most of the patients (80%). In the whole cohort, 79.1% of the patients had complete recovery. Gas-filled pseudocysts are rarely observed in daily practice. They present mostly in men at the age of 60s. Precise differential diagnosis determination using appropriate imaging would help clinicians treat the patients properly. Gas-filled pseudocysts should be treated similarly to other spinal pathologies causing nerve root compression. © 2022 Elsevier B.V., All rights reserved.