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Publication Open Access Fracture and migration of a retained microcatheter into the cauda equina after endovascular neurointervention for dural arteriovenous fistula as a rare cause of tethered spinal cord: Case report(American Association of Neurological Surgeons, 2020) Demirci Otluoglu, Gulden; Hasanov, Teyyub; Mert, Başak; Toktaş, Zafer Orkun; Konya, Deniz; Demir, Mustafa Kemal; Demirci Otluoglu, Gulden, Department of Neurosurgery, Bahçeşehir Üniversitesi, Istanbul, Turkey; Hasanov, Teyyub, Department of Neurosurgery, Bahçeşehir Üniversitesi, Istanbul, Turkey; Mert, Başak, Bahçeşehir Üniversitesi, Istanbul, Turkey; Toktaş, Zafer Orkun, Department of Neurosurgery, Bahçeşehir Üniversitesi, Istanbul, Turkey; Konya, Deniz, Department of Neurosurgery, Bahçeşehir Üniversitesi, Istanbul, Turkey; Demir, Mustafa Kemal, Department of Radiology, Bahçeşehir Üniversitesi, Istanbul, TurkeyThe evaluation of spinal cord vascular malformations in neuroradiology departments remains valid for both diagnosis and endovascular embolization, and for adjuvant as well as definitive treatment. The most commonly encountered complications of endovascular approaches are the recurrence or the incomplete embolization of the lesion and accidental damage to the medullary arteries, which leads to spinal cord infarction. Failure to remember a microcatheter in the abdominal aorta after catheterization is an underestimated complication. A retained guidewire in the circulation may not necessarily cause symptoms, and it may remain unnoticed for a significant period of time. However, severe complications may be faced even many years later. In this article, a case report on a fracture and migration of a retained microcatheter in the cauda equina is presented. This occurred after an endovascular neurointervention for dural arteriovenous fistula as a rare cause of tethered spinal cord. © 2020 Elsevier B.V., All rights reserved.Publication Metadata only Encephalomyelitis associated with Covid-19 infection: case report(Taylor and Francis Ltd, 2020) Demirci Otluoglu, Gulden; Yener, Ulaş; Demir, Mustafa Kemal; Yilmaz, Baran; Demirci Otluoglu, Gulden, Department of Neurosurgery, Bahçeşehir Üniversitesi, Istanbul, Turkey; Yener, Ulaş, Department of Neurosurgery, University of Virginia, Charlottesville, United States; Demir, Mustafa Kemal, Department of Radiology, Bahçeşehir Üniversitesi, Istanbul, Turkey; Yilmaz, Baran, Department of Neurosurgery, Bahçeşehir Üniversitesi, Istanbul, TurkeyWe describe a COVID-19 patient who presented with persistent headache and anosmia that was related to viral encephalomyelitis with acute lesions on MRI in both the brain and upper cervical cord. © 2020 Elsevier B.V., All rights reserved.Publication Open Access Primary Sonic Hedgehog–activated dorsal brainstem medulloblastoma and ipsilateral cerebellar atrophy in an adult(SAGE Publications Inc., 2020) Demir, Mustafa Kemal; Kurtkaya-Yapicier, Özlem Sahan; Mert, Başak; Alshareefi, Wiaam; Bozbuǧa, Mustafa; Demir, Mustafa Kemal, Department of Radiology, Bahçeşehir Üniversitesi, Istanbul, Turkey; Kurtkaya-Yapicier, Özlem Sahan, Department of Pathology, Bahçeşehir Üniversitesi, Istanbul, Turkey; Mert, Başak, Bahçeşehir Üniversitesi, Istanbul, Turkey; Alshareefi, Wiaam, Bahçeşehir Üniversitesi, Istanbul, Turkey; Bozbuǧa, Mustafa, Department of Neurosurgery, Üsküdar Üniversitesi, Istanbul, TurkeyMedulloblastoma (MB) that arises outside the cerebellum from cells of the dorsal brainstem is rare. The most common subtype of MB in the dorsal brainstem is the Wingless (WNT) subtype that contains activating mutations in the WNT pathway effector CTNNB1. Ipsilateral cerebellar hemi-atrophy with a brainstem tumour is a finding that is usually documented with brainstem gangliogliomas as a possible specific imaging sign. We present a case of a 23-year-old female with progressive headache, imbalance on walking, double vision and difficulty in swallowing for a year. Magnetic resonance imaging demonstrated a mass with prominent restricted diffusion on the dorsal surface of the lower brainstem with ipsilateral cerebellar atrophy. The final histopathological diagnosis was a Sonic Hedgehog (SHH)-activated and TP53 wild-type primary lower dorsal brainstem MB. Primary SHH-activated TP53 wild-type dorsal brainstem MB is extremely rare, and as far as we know, the association of the tumour with ipsilateral cerebellar hemi-atrophy in an adult has never been reported. MB should be included in the differential diagnosis of focal dorsal brainstem tumours, even in the presence of ipsilateral cerebellar hemi-atrophy. © 2022 Elsevier B.V., All rights reserved.Publication Metadata only A primary third ventricle mixed germ cell tumor with leptomeningeal dissemination of immature teratoma component(Springer, 2020) Demir, Mustafa Kemal; Kurtkaya-Yapicier, Özlem Sahan; Karakaya, Omer Faruk; Mert, Başak; Şeker, Aśkin N.; Demir, Mustafa Kemal, Department of Radiology, Bahçeşehir Üniversitesi, Istanbul, Turkey; Kurtkaya-Yapicier, Özlem Sahan, Department of Pathology, Bahçeşehir Üniversitesi, Istanbul, Turkey; Karakaya, Omer Faruk, Bahçeşehir Üniversitesi, Istanbul, Turkey; Mert, Başak, Bahçeşehir Üniversitesi, Istanbul, Turkey; Şeker, Aśkin N., Department of Neurosurgery, Altinbas Universitesi, Istanbul, TurkeyA 17-year-old male patient presented to the clinic with a headache, nausea, and vomiting. Magnetic resonance imaging demonstrated a fat-containing and -enhancing heterogeneous tumor in the third ventricle, and fat droplets within the ventricles and the subarachnoid space. Obstructive hydrocephalus was also present. Emergency subtotal removal of the mass was performed via interhemispheric transcallosal approach. The histopathological diagnosis was a mixed germ cell tumor that was composed of embryonal carcinoma, yolk-sac tumor, germinoma, and immature teratoma containing a large amount of mature elements. The patient was referred for postoperative chemoradiotherapy. A mixed germ cell tumor is a rare type of nongerminomatous germ cell tumor that is made up of at least two different types of germ cell tumors. These may include germinoma, choriocarcinoma, embryonal carcinoma, yolk sac tumor, mature teratoma, immature teratoma, or teratoma with malignant degeneration. As far as we know, this is the first reported case of a primary third ventricle mixed germ cell tumor with leptomeningeal dissemination of the immature teratoma component that contains grossly visible mature elements at admission. © 2020 Elsevier B.V., All rights reserved.Publication Metadata only A diagnostic dilemma in the emergency room: intracranial hemorrhages in acute myeloblastic leukemia with hyperleukocytosis(Springer, 2020) Demir, Mustafa Kemal; Demir, Mustafa Kemal, Department of Radiology, Bahçeşehir Üniversitesi, Istanbul, Turkey[No abstract available]Publication Metadata only Mesial temporal lobe rosette-forming glioneuronal tumor : an unusual location for a rare tumor(Springer, 2020) Kurtkaya-Yapicier, Özlem Sahan; Demir, Mustafa Kemal; Jaafar, Ebrahim; Bozbuǧa, Mustafa; Kurtkaya-Yapicier, Özlem Sahan, Department of Pathology, Bahçeşehir Üniversitesi, Istanbul, Turkey; Demir, Mustafa Kemal, Department of Radiology, Bahçeşehir Üniversitesi, Istanbul, Turkey; Jaafar, Ebrahim, Bahçeşehir Üniversitesi, Istanbul, Turkey; Bozbuǧa, Mustafa, Department of Neurosurgery, Üsküdar Üniversitesi, Istanbul, Turkey[No abstract available]Publication Open Access Morphometry of common carotid artery and internal jugular vein in relation to gender and body side, Arteria Carotis Communis ve Vena Jugularis Interna'nin Cinsiyet ve Vücut Tarafina göre Morfometrisi(Gazi Universitesi mmfd@gazi.edu.tr, 2020) Ertem, Onder; Demir, Mustafa Kemal; Barut, Cagatay; Ertem, Onder, Bahçeşehir Üniversitesi, Istanbul, Turkey; Demir, Mustafa Kemal, Department of Radiology, Bahçeşehir Üniversitesi, Istanbul, Turkey; Barut, Cagatay, Department of Anatomy, Bahçeşehir Üniversitesi, Istanbul, TurkeyIntroduction: The common carotid arteries originate from brachiocephalic trunk on the right and directly from the aortic arch on the left. These arteries are contained within the carotid sheaths together with the internal jugular veins and vagus nerves. The structures enclosed in carotid sheath are of great importance, since they provide most of the vascular supply of the head and neck. They exhibit a great deal of variation and are related with a number of pathologic conditions and invasive procedures. Objectives: Thus we focused on morphology of the common carotid artery (CCA) and internal jugular vein (IJV) to determine these possible variations. Methods: Neck magnetic resonance images of 81 individuals (38 females and 43 males) were evaluated retrospectively. Diameter of the lumen of the common carotid artery (CD) and the diameters of the lumen of the internal jugular vein (ID) were measured at the same level that is one slice inferior to the slice in which the bifurcation of the CCA is observed firstly. CCA intima-media thickness (CIMT), IJV intima-media thickness (IIMT), CCA-midline distance (CMD) and IJV-midline distance (IMD) were also measured at the aforementioned level. The measurements were evaluated in relation to gender and asymmetry. Results: The values measured for Right CMD, Right IMD, Left CD, Left CMD and Left IMD of males were greater than those of females (p<0.05). The results stressed various morphometric parameters and topography of the IJV and CCA. Conclusion: The results are suggested to be helpful in determination of normal values in terms of diagnostic purposes and treatment planning. © 2020 Elsevier B.V., All rights reserved.Publication Metadata only Cerebral hydatid disease with serpent sign, calcifications, and peripheral enhancement(Springer Science and Business Media Deutschland GmbH info@springer-sbm.com, 2020) Demir, Mustafa Kemal; Kurtkaya-Yapicier, Özlem Sahan; Jameel, Muslim Ageel; Bozbuǧa, Mustafa; Demir, Mustafa Kemal, Department of Radiology, Bahçeşehir Üniversitesi, Istanbul, Turkey; Kurtkaya-Yapicier, Özlem Sahan, Department of Pathology, Bahçeşehir Üniversitesi, Istanbul, Turkey; Jameel, Muslim Ageel, Bahçeşehir Üniversitesi, Istanbul, Turkey; Bozbuǧa, Mustafa, Department of Neurosurgery, Üsküdar Üniversitesi, Istanbul, Turkey[No abstract available]Publication Metadata only Red cell distribution width levels in Parkinson’s disease patients(Springer Science and Business Media Deutschland GmbH info@springer-sbm.com, 2020) Kenangil, Gülay Ozgen; Ari, Buse Cagla; Kaya, Fatma Altuntaş; Demir, Mustafa Kemal; Mayda-Domaç, Füsun; Kenangil, Gülay Ozgen, Department of Neurology, Bahçeşehir Üniversitesi, Istanbul, Turkey; Ari, Buse Cagla, Department of Neurology, Erenköy Mental Health and Neurological Diseases Training and Research Hospital, Istanbul, Turkey; Kaya, Fatma Altuntaş, Department of Neurology, Erenköy Mental Health and Neurological Diseases Training and Research Hospital, Istanbul, Turkey; Demir, Mustafa Kemal, Department of Neurology, Erenköy Mental Health and Neurological Diseases Training and Research Hospital, Istanbul, Turkey; Mayda-Domaç, Füsun, Department of Neurology, Erenköy Mental Health and Neurological Diseases Training and Research Hospital, Istanbul, TurkeyParkinson’s disease (PD) is a neurodegenerative disorder with motor and non-motor impairment. It has been known for a while that oxidative stress, protein changes and mitochondrial dysfunction have the role of contribution to the pathogenesis. Disturbance of red blood cell function may play a role in the pathophysiology of neurodegenerative diseases such as Huntington’s, Parkinson’s and Alzheimer’s disease. RDW was found to be strongly associated with inflammatory markers in diseases such as acute pancreatitis, myocardial injury and hepatocellular carcinoma. The data about RDW levels and PD are scarce. In this study, we aimed to investigate the RDW values and their relationship with the severity of the disease in patients with Parkinson’s disease. 94 patients with Parkinson’s disease were included into the study, 97 healthy individuals without history of PD were considered as control group. The United Parkinson’s Disease Rating Scale (UPDRS) and the modified Hoehn and Yahr staging scale were used to assess the severity of PD. Although RDW levels were significantly higher than the healthy subjects, there was not any relation between the severity of PD, duration of the disease, RDW levels, other blood parameters, mean UPDRS score or mean mH&Y score. In conclusion, RDW levels are higher than the healthy subjects in PD patients but there is no relation between RDW levels and disease duration. Larger studies are needed to explain the role of RDW as an inflammatory marker. © 2020 Elsevier B.V., All rights reserved.Publication Metadata only Intracranial extra-axial mesenchymal chondrosarcoma in a 16-month-old patient with a literature review of pediatric patients(Springer Science and Business Media Deutschland GmbH, 2021) Kurtkaya-Yapicier, Özlem Sahan; Nanah, Abdelrahman; Taşkapılıoğlu, Mevlüt Özgür; Demir, Mustafa Kemal; Kurtkaya-Yapicier, Özlem Sahan, Department of Pathology, Bahçeşehir Üniversitesi, Istanbul, Turkey; Nanah, Abdelrahman, Bahçeşehir Üniversitesi, Istanbul, Turkey; Taşkapılıoğlu, Mevlüt Özgür, Department of Neurosurgery, Bursa Uludağ Üniversitesi, Bursa, Turkey; Demir, Mustafa Kemal, Department of Radiology, Bahçeşehir Üniversitesi, Istanbul, TurkeyMesenchymal chondrosarcoma is a rare high-grade malignant subtype of chondrosarcoma that is characterized by undifferentiated, round, or spindled mesenchymal cells, interspersed with islands of hyaline cartilage. We report a primary intracranial extra-axial mesenchymal chondrosarcoma in a 16-month-old patient with a review of the literature focusing on intracranial extra-axial MCs with or without skull involvement in pediatric patients, including differential diagnosis. The patient was admitted with a swelling in the right temporooccipital region. There was intracranial extra-dural extension of the mass, which abuts the neural parenchyma without any invasion. A complete tumor resection was performed. Pathological diagnosis was mesenchymal chondrosarcoma. The patient was free of symptoms after surgery. © 2021 Elsevier B.V., All rights reserved.