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Publication Metadata only Sex matters in CSU: Women face greater burden and poorer urticaria control, especially in midlife-CURE insights(WILEY, 2025) Kocaturk, Emek; Salameh, Pascale; Asero, Riccardo; Bizjak, Mojca; Gimenez-Arnau, Ana; Grattan, Clive; Pesque, David; Planella-Fontanillas, Nidia; Herzog, Leonie Shirin; Buttgereit, Thomas; Bonnekoh, Hanna; Fomina, Daria; Kovalkova, Elena; Lebedkina, Marina; Kasperska-Zajac, Alicja; Zajac, Magdalena; Zamlynsk, Mateusz; Kulthanan, Kanokvalai; Tuchinda, Papapit; Khoshkhui, Maryam; Hassanpour, Zohreh; Peter, Jonny; Du-Thanh, Aurelie; Meshkova, Raisa; Abuzakouk, Mohamed; Makris, Michael; Bouillet, Laurence; Bocquet, Alexis; Gregoriou, Stamatios; Thomsen, Simon Francis; Dissemond, Joachim; Staubach, Petra; Bauer, Andrea; Danilycheva, Inna; van Doorn, Martijn; Parisi, Claudio; Metz, Martin; Fluhr, Joachim W.; Zuberbier, Torsten; Weller, Karsten; Kolkhir, Pavel; Free University of Berlin; Humboldt University of Berlin; Charite Universitatsmedizin Berlin; Free University of Berlin; Humboldt University of Berlin; Bahcesehir University; Lebanese American University; University of Nicosia; University Clinic Golnik; Pompeu Fabra University; Hospital del Mar Research Institute; Hospital del Mar; Sechenov First Moscow State Medical University; Astana Medical University; Medical University of Silesia; Mahidol University; Mashhad University of Medical Sciences; Ahvaz Jundishapur University of Medical Sciences (AJUMS); University of Cape Town; Universite de Montpellier; Cleveland Clinic Foundation; National & Kapodistrian University of Athens; University Hospital Attikon; CHU Grenoble Alpes; Communaute Universite Grenoble Alpes; Universite Grenoble Alpes (UGA); National & Kapodistrian University of Athens; University of Copenhagen; Copenhagen University Hospital; Bispebjerg Hospital; University of Copenhagen; University of Duisburg Essen; Johannes Gutenberg University of Mainz; Technische Universitat Dresden; Carl Gustav Carus University Hospital; NRC Institute of Immunology FMBA of Russia; Erasmus University Rotterdam; Erasmus MC; Hospital Italiano de Buenos Aires; University of Buenos Aires; University of Buenos Aires HospitalBackground: Chronic spontaneous urticaria (CSU), a disease predominantly affecting females, has limited information available on its differences between females and males of varying ages.Objective To investigate sex differences in age groups regarding disease activity, comorbidities, quality of life (QoL) and treatment patterns in CSU patients. Methods: We analysed Chronic Urticaria Registry (CURE) data, an international real-world registry for patients with chronic urticaria. Patients were recruited via an online platform using a standardized questionnaire. The data were analysed for demographics, age of onset, duration of urticaria, (Urticaria Activity Score [UAS], Urticaria Control Test [UCT], Chronic Urticaria Quality of Life Questionnaire [CU-Q2oL]), family history, systemic symptoms, aggravating factors, comorbidities, smoking and alcohol consumption, laboratory parameters, burden of disease, treatment distribution and response rates, compliance to treatment and adverse events. Comparisons were made among age groups <13, 13-17, 18-30, 31-50, 51-65 and >65 years. Results: Across 4136 CSU patients (from 58 sites across 29 countries), 2994 (72.4%) were female. Statistically significant female predominance started at age 31 (<0.001). Compared with males, females showed higher rates of angioedema (59.6 vs. 51.7%, p < 0.001), systemic symptoms (34.6 vs. 25.4%, p < 0.001), sleep disturbance (38.9 vs. 32.5%, p < 0.001), QoL impairment (CU-Q2oL score 32 vs. 27.7, p < 0.001) and lower rates of urticaria control than males in all medication categories (p < 0.05 for all). Females had more concomitant diseases, including asthma, thyroid disease, obesity, autoimmune disease, gastrointestinal disease and depression (p < 0.05 for all). The disease was especially more burdensome and refractory in females aged 51-65 years than males, evidenced by more angioedema and systemic symptoms, worse QoL, lower UCT scores and more emergency visits (p < 0.05 for all). However, these differences were not prominent in the elderly females (>65 years).Conclusion Compared with males, female CSU patients experience more burdensome disease, which gets worse in midlife.Publication Metadata only Response to Reflections on ultrasound-guided biceps femoris short head (BiFeS) block(OXFORD UNIV PRESS, 2025) Tulgar, Serkan; Kilicaslan, Alper; Ahiskalioglu, Ali; Bahcesehir University; Necmettin Erbakan University; Ataturk UniversityPublication Metadata only In vitro Chondrogenic Induction Promotes the Expression Level of IL-10 via the TGF-β/SMAD and Canonical Wnt/β-catenin Signaling Pathways in Exosomes Secreted by Human Adipose Tissue-derived Mesenchymal Stem Cells (vol 82, pg 3741, 2024)(HUMANA PRESS INC, 2025) Sevimli, Tugba Semerci; Inan, Ulukan; Mantar, Dilara; Guler, Kubra; Ahmadova, Zarifa; Gulec, Kadri; Topal, Ahmet Emin; Eskisehir Osmangazi University; Eskisehir Osmangazi University; Erzurum Technical University; Bahcesehir University; Ruprecht Karls University Heidelberg; Anadolu UniversityPublication Metadata only Mind the Gap: Perceived Economic Inequality and the Well-Being Gap around the Globe(SAGE PUBLICATIONS INC, 2025) Sanchez-Rodriguez, Angel; Gorski, Maciej R.; Joshanloo, Mohsen; Krys, Kuba; Tonnessen, Morten; Li, Liman Man Wai; Akaliyski, Plamen; Haas, Brian W.; Hussain, M. Azhar; Guemaz, Farida; Boussena, Mahmoud; Iter, Nuha; Vlasenko, Olha; Lun, Vivian Miu-Chi; Vignoles, Vivian L.; Aminnuddin, Nur Amali; Isik, Idil; Ngom-Dieng, Laina; Fulop, Marta; Igbokwe, David; Adamovic, Mladen; Garoarsdottir, Ragna Benedikta; Soboleva, Natalia; Teyssier, Julien; Gluckstad, Fumiko Kano; Park, Joonha; Zelenski, John; Yeung, Victoria Wai Lan; Yeung, June Chun; Yau, Eric Kenson; Yang, Jae-Won; Yakhlef, Belkacem; Xing, Cai; Wasiel, Arkadiusz; Vauclair, Christin-Melanie; van Tilburg, Wijnand; Turjacanin, Vladimir; Tra, Kieu Thi Thanh; Torres, Claudio; Sun, Chien-Ru; Sokolov, Boris; Sobhie, Rosita; Sirlopu, David; Selim, Heyla; Rocha, Ana Maria; Rizwan, Muhammad; Solcova, Iva Polackova; Pavlovic, Zoran; Palikot, Ewa; Olechowski, Mateusz; Okvitawanli, Ayu; Ochoa, Danielle; Nowak, Kaeolina; Nader, Martin; Myslinska-Szarek, Katarzyna; Murdock, Elke; Mosca, Oriana; Mosanya, Magdalena; Mokadem, Fatma; Mohammed, Linda; Malyonova, Arina; Malyonov, Alexander; Lee, Hannah; Lauri, Mary Anne; Kronberger, Nicole; Kocimska-Bortnowska, Agata; Kluzowicz, Maria; Kascakova, Natalia; Imran, Mostak Ahamed; Igou, Eric Raymond; Henk, Katharina; Hasanov, Rafail; Gjoneska, Biljana; Gavreliuc, Alin; Garvanova, Magdalena; Gamsakhurdia, Vladimer; Espinosa, Agustin; Dominguez Espinosa, Alejandra; Deltour, Jule; Costin, Vlad; Bolatov, Aidos; Baltin, Arno; Bakyono-Nabaloum, Rasmata; Asif, Resham; Appoh, Lily; Anic, Petra; Andrade, Laura; Almakaeva, Anna; Al-Zoubi, Marwan; Akello, Grace; Bond, Michael Harris; University of Salamanca; Polish Academy of Sciences; Institute of Psychology of the Polish Academy of Sciences; University of Warsaw; Keimyung University; Universitetet i Stavanger; Education University of Hong Kong (EdUHK); Lingnan University; University System of Georgia; University of Georgia; University of Sharjah; Roskilde University; Palestine Technical University - Kadoorie; University Osnabruck; University of Sussex; University Brunei Darussalam; Bahcesehir University; University Cheikh Anta Diop Dakar; University of London; King's College London; University of Iceland; HSE University (National Research University Higher School of Economics); Universite de Toulouse; Copenhagen Business School; Kyoto University; Carleton University; Catholic University of Korea; Ecole Normale Superieure de Constantine; Renmin University of China; Instituto Universitario de Lisboa; University of Essex; University of Banja Luka (UNIBL); Universidade de Brasilia; National Chengchi University; Anton de Kom Universiteit van Suriname; Universidad San Sebastian; King Saud University; Czech Academy of Sciences; Institute of Psychology of the Czech Academy of Sciences; University of Belgrade; Sebelas Maret University; University of the Philippines System; University of the Philippines Diliman; Universidad ICESI; University of Luxembourg; University of Cagliari; Dostoevsky Omsk State University; Indiana University System; Indiana University Northwest; University of Malta; Johannes Kepler University Linz; Palacky University Olomouc; Bangladesh Rural Advancement Committee BRAC; BRAC University; University of Limerick; University of Koblenz & Landau; Ministry of Education of Azerbaijan Republic; Baku State University; West University of Timisoara; University for Library Studies & Information Technology; Ivane Javakhishvili Tbilisi State University; Pontificia Universidad Catolica del Peru; Universidad Iberoamericana Ciudad de Mexico; Astana Medical University; Tallinn University; Universite Joseph Ki-Zerbo; Nord University; University of Rijeka; University of Jordan; Gulu University; Hong Kong Polytechnic UniversityThe link between economic inequality and individual well-being has been gaining increasing research attention. This study examines this relationship using data from 71 countries with diverse national incomes, addressing three key research gaps: (1) incorporating measures of both perceived and objective economic inequality, (2) extending analysis to multiple components of well-being beyond happiness, including meaning in life, harmony, and spirituality, and (3) assessing levels of both current and ideal well-being. Findings reveal that perceived economic inequality predicts personal well-being more strongly than objective inequality. In addition, perceived inequality is associated with a wider gap between current and ideal levels of happiness, meaning, harmony, and spirituality, although national income moderates the effects of meaning, harmony, and spirituality. We discuss the implications of these results, highlighting the need for more culturally sensitive studies on perceived economic inequality and well-being.Publication Metadata only Sex matters in CSU: Women face greater burden and poorer urticaria control, especially in midlife-CURE insights(WILEY, 2025) Kocaturk, Emek; Salameh, Pascale; Asero, Riccardo; Bizjak, Mojca; Gimenez-Arnau, Ana; Grattan, Clive; Pesque, David; Planella-Fontanillas, Nidia; Herzog, Leonie Shirin; Buttgereit, Thomas; Bonnekoh, Hanna; Fomina, Daria; Kovalkova, Elena; Lebedkina, Marina; Kasperska-Zajac, Alicja; Zajac, Magdalena; Zamlynsk, Mateusz; Kulthanan, Kanokvalai; Tuchinda, Papapit; Khoshkhui, Maryam; Hassanpour, Zohreh; Peter, Jonny; Du-Thanh, Aurelie; Meshkova, Raisa; Abuzakouk, Mohamed; Makris, Michael; Bouillet, Laurence; Bocquet, Alexis; Gregoriou, Stamatios; Thomsen, Simon Francis; Dissemond, Joachim; Staubach, Petra; Bauer, Andrea; Danilycheva, Inna; van Doorn, Martijn; Parisi, Claudio; Metz, Martin; Fluhr, Joachim W.; Zuberbier, Torsten; Weller, Karsten; Kolkhir, Pavel; Free University of Berlin; Humboldt University of Berlin; Charite Universitatsmedizin Berlin; Free University of Berlin; Humboldt University of Berlin; Bahcesehir University; Lebanese American University; University of Nicosia; University Clinic Golnik; Pompeu Fabra University; Hospital del Mar Research Institute; Hospital del Mar; Sechenov First Moscow State Medical University; Astana Medical University; Medical University of Silesia; Mahidol University; Mashhad University of Medical Sciences; Ahvaz Jundishapur University of Medical Sciences (AJUMS); University of Cape Town; Universite de Montpellier; Cleveland Clinic Foundation; National & Kapodistrian University of Athens; University Hospital Attikon; CHU Grenoble Alpes; Communaute Universite Grenoble Alpes; Universite Grenoble Alpes (UGA); National & Kapodistrian University of Athens; University of Copenhagen; Copenhagen University Hospital; Bispebjerg Hospital; University of Copenhagen; University of Duisburg Essen; Johannes Gutenberg University of Mainz; Technische Universitat Dresden; Carl Gustav Carus University Hospital; NRC Institute of Immunology FMBA of Russia; Erasmus University Rotterdam; Erasmus MC; Hospital Italiano de Buenos Aires; University of Buenos Aires; University of Buenos Aires HospitalBackground: Chronic spontaneous urticaria (CSU), a disease predominantly affecting females, has limited information available on its differences between females and males of varying ages.Objective To investigate sex differences in age groups regarding disease activity, comorbidities, quality of life (QoL) and treatment patterns in CSU patients. Methods: We analysed Chronic Urticaria Registry (CURE) data, an international real-world registry for patients with chronic urticaria. Patients were recruited via an online platform using a standardized questionnaire. The data were analysed for demographics, age of onset, duration of urticaria, (Urticaria Activity Score [UAS], Urticaria Control Test [UCT], Chronic Urticaria Quality of Life Questionnaire [CU-Q2oL]), family history, systemic symptoms, aggravating factors, comorbidities, smoking and alcohol consumption, laboratory parameters, burden of disease, treatment distribution and response rates, compliance to treatment and adverse events. Comparisons were made among age groups <13, 13-17, 18-30, 31-50, 51-65 and >65 years. Results: Across 4136 CSU patients (from 58 sites across 29 countries), 2994 (72.4%) were female. Statistically significant female predominance started at age 31 (<0.001). Compared with males, females showed higher rates of angioedema (59.6 vs. 51.7%, p < 0.001), systemic symptoms (34.6 vs. 25.4%, p < 0.001), sleep disturbance (38.9 vs. 32.5%, p < 0.001), QoL impairment (CU-Q2oL score 32 vs. 27.7, p < 0.001) and lower rates of urticaria control than males in all medication categories (p < 0.05 for all). Females had more concomitant diseases, including asthma, thyroid disease, obesity, autoimmune disease, gastrointestinal disease and depression (p < 0.05 for all). The disease was especially more burdensome and refractory in females aged 51-65 years than males, evidenced by more angioedema and systemic symptoms, worse QoL, lower UCT scores and more emergency visits (p < 0.05 for all). However, these differences were not prominent in the elderly females (>65 years).Conclusion Compared with males, female CSU patients experience more burdensome disease, which gets worse in midlife.Publication Metadata only Isolated infantile myofibroma of the calvarium: Report of a case with a literature review (Jan, 10.1007/s00381-024-06289-9, 2024)(SPRINGER, 2024) Demir, Mustafa Kemal; Yapicier, Ozlem; Celik, Ozgur; Ertem, Onder; Kilic, Deniz; Bahcesehir University; Medical Park Hospitals Group; Bahcesehir University; Medical Park Hospitals Group; Near East UniversityPublication Metadata only Global Andrology Forum Clinical Guidelines on the Relevance of Sperm DNA Fragmentation in Medicine(KOREAN SOC SEXUAL MEDICINE & ANDROLOGY, 2025) Cayan, Selahittin; Farkouh, Ala'a; Agarwal, Ashok; Atmoko, Widi; Wyns, Christine; Arafa, Mohamed; Zini, Armand; Shah, Rupin; Alipour, Hiva; Chung, Eric; Saleh, Ramadan; Pinggera, Germar-Michael; Konstantinidis, Charalampos; Al Hashimi, Manaf; Pescatori, Edoardo; Rambhatla, Amarnath; Toprak, Tuncay; Calogero, Aldo E.; Gul, Murat; Park, Hyun Jun; Altay, Baris; Falcone, Marco; Rashed, Ayman; Le, Tan V.; Bahar, Fahmi; Shatylko, Taras; Gorur, Sadik; El-Sakka, Ahmed I.; Saylam, Bari; Sarikaya, Selcuk; Smith, Ryan Patrick; Boeri, Luca; Efesoy, Ozan; Ceyhan, Erman; Russo, Giorgio Ivan; Ozer, Cevahir; Ho, Christopher Chee Kong; Gungor, Nur Dokuzeylul; Ozlu, Deniz Noyan; Molina, Juan Manuel Corral; Musa, Muhammad Ujudud; Tsujimura, Akira; Gokalp, Fatih; Mohamed, Mohamed Saeed; Okada, Keisuke; Khalafalla, Kareim; Kuroda, Shinnosuke; Binsaleh, Saleh; Motawi, Ahmad Tarek; Shamohammadi, Iman; Mogharabian, Nasser; Manh, Manh Truong; Taha, Emad Abdelraheem; Makarounis, Konstantinos; Mak, Siu King; Shedeed, Shedeed Ashour; Thomas, Charalampos; Mostafa, Taymour; Mersin University; Loma Linda University; Cleveland Clinic Foundation; University of Indonesia; Dr. Cipto Mangunkusumo National Public Hospital; Universite Catholique Louvain; Cliniques Universitaires Saint-Luc; Universite Catholique Louvain; Egyptian Knowledge Bank (EKB); Cairo University; Hamad Medical Corporation; Qatar Foundation (QF); Weill Cornell Medical College Qatar; McGill University; Aalborg University; Princess Alexandra Hospital; University of Queensland; Egyptian Knowledge Bank (EKB); Sohag University; Medical University of Innsbruck; Khalifa University of Science & Technology; Henry Ford Health System; Henry Ford Hospital; Michigan State University; Michigan State University College of Human Medicine; University of Health Sciences Turkey; University of Catania; Selcuk University; Selcuk University; Pusan National University; Pusan National University; Pusan National University Hospital; Ege University; A.O.U. Citta della Salute e della Scienza di Torino; University of Turin; Biruni University; Egyptian Knowledge Bank (EKB); October 6 University (O6U); Hatay Mustafa Kemal University; Egyptian Knowledge Bank (EKB); Suez Canal University; Gulhane Training & Research Hospital; University of Health Sciences Turkey; University of Virginia; IRCCS Ca Granda Ospedale Maggiore Policlinico; Baskent University; University of Catania; Baskent University; Taylor's University; Bahcesehir University; University of Health Sciences Turkey; Bakirkoy Dr. Sadi Konuk Research & Training Hospital; University of Barcelona; Hospital Clinic de Barcelona; Juntendo University; Egyptian Knowledge Bank (EKB); Al Azhar University; Kobe University; Qatar University; Yokohama City University; King Saud University; Shiraz University of Medical Science; Shahroud University Medical Sciences; Egyptian Knowledge Bank (EKB); Assiut University; Egyptian Knowledge Bank (EKB); Assiut UniversityPurpose: To evaluate the evidence on sperm DNA fragmentation (SDF) and its clinical applications in reproductive medicine, highlighting benefits, limitations, and guidelines for its use to assist clinicians in objective decision-making. Materials and Methods: A multidisciplinary team of clinicians and reproductive experts from the Global Andrology Forum (GAF) reviewed the latest evidence on SDF, covering indications, testing methods, recurrent pregnancy loss, varicocele and its repair, assisted reproductive technologies (ART), treatment of associated conditions, antioxidant therapy, and sperm selection for ART. Expert statements and recommendations were developed and graded with the GRADE system using a modified Delphi process. Results: Based on the GAF surveys, systematic reviews, and meta-analyses related to SDF, 52 experts introduced and scored 24 statements and recommendations using the GRADE system. Of these, 87.5% (21/24) achieved strong ratings, reflecting broad consensus, while 12.5% (3/24) were rated weak. The guidelines provide evidence-based recommendations for clinical scenarios, including the role of SDF in infertility, recurrent pregnancy loss, and ART outcomes. Conclusions: While there is growing interest and evidence regarding the clinical benefit of SDF testing and its utility in managing male infertility, significant gaps in the literature limit its routine use in clinical practice. The guidelines offer a structured framework for integrating SDF testing into male infertility management, emphasizing a tailored approach based on individual clinical scenarios. Clinicians must balance the benefits and limitations of SDF testing and antioxidant treatment to optimize care in reproductive medicine. These guidelines are critical for advancing evidence-based practices in male infertility management.Publication Metadata only Mucosal angioedema involving the oropharynx signals severe cold urticaria: COLD-CE study insights(WILEY, 2025) Bizjak, Mojca; Fomina, Daria; Peter, Jonny; Gimenez-Arnau, Ana Maria; Pesque, David; Goncalo, Margarida; Aarestrup, Fernando Monteiro; Ahsan, Dalia Melina; Al-Ahmad, Mona; Altrichter, Sabine; Andrenova, Gerelma; Bauer, Andrea; Borzova, Elena; Costa, Celia; Fachini Criado, Roberta; Demir, Semra; Dinevski, Dejan; Ensina, Luis Felipe; Gelincik, Asli; Gotua, Maia; Holm, Jesper Gronlund; Inomata, Naoko; Khoshkhui, Maryam; Klyucharova, Aliya; Kocatuerk, Emek; Kosnik, Mitja; Kulthanan, Kanokvalai; de Souza Lima, Eduardo M.; Lu, Rongbiao; Makris, Michael; Meshkova, Raisa; Pasali, Maria; Paulino, Marisa; Ramon, German Dario; Ritchie, Carla; Rudenko, Michael; Thomsen, Simon Francis; Rodrigues Valle, Solange Oliveira; Wagner, Nicola; Xepapadaki, Paraskevi; Xue, Xiaoyang; Kasperska-Zajac, Alicja; Zhao, Zuotao; Terhorst-Molawi, Dorothea; University Clinic Golnik; University of Ljubljana; Sechenov First Moscow State Medical University; University of Cape Town; University of Cape Town; Pompeu Fabra University; Hospital del Mar Research Institute; Hospital del Mar; Hospital del Mar Research Institute; Hospital del Mar; Autonomous University of Barcelona; Hospital Universitari Vall d'Hebron; Universidade de Coimbra; Centro Hospitalar e Universitario de Coimbra (CHUC); Humboldt University of Berlin; Free University of Berlin; Charite Universitatsmedizin Berlin; Berlin Institute of Health; Kuwait University; Kepler University Hospital; Johannes Kepler University Linz; Technische Universitat Dresden; Carl Gustav Carus University Hospital; Niigata University; Universidade de Lisboa; Hospital Santa Maria; Faculdade de Medicina do ABC; Istanbul University; University of Maribor; Universidade Federal de Sao Paulo (UNIFESP); University of Copenhagen; Copenhagen University Hospital; Bispebjerg Hospital; Yokohama City University; Mashhad University of Medical Sciences; Kazan Federal University; Bahcesehir University; Mahidol University; Sun Yat Sen University; National & Kapodistrian University of Athens; University Hospital Attikon; University of Buenos Aires; University of Buenos Aires Hospital; Hospital Italiano de Buenos Aires; Universidade Federal do Rio de Janeiro; University of Erlangen Nuremberg; National & Kapodistrian University of Athens; Community Health Service Center; Medical University of SilesiaPublication Metadata only Expanding the indication of living donor liver transplantation to recipients with PVT: Clinical advances and ongoing challenges(LIPPINCOTT WILLIAMS & WILKINS, 2025) Balci, Deniz; Gomez-Gavara, Concepcion; Hessheimer, Amelia J.; Bahcesehir University; Hospital Universitari Vall d'Hebron; CIBER - Centro de Investigacion Biomedica en Red; CIBEREHD; Hospital Universitario La PazPublication Metadata only Response to BiFeS block: Distinction or redundancy?(OXFORD UNIV PRESS, 2025) Ahiskalioglu, Ali; Tulgar, Serkan; Kilicaslan, Alper; Ataturk University; Bahcesehir University; Necmettin Erbakan University