Publication:
Design and numeric evaluation of a novel axial-flow left ventricular assist device

dc.contributor.authorToptop, Koral
dc.contributor.authorKadipaşaoǧlu, Kâmuran A.
dc.contributor.institutionToptop, Koral, Department of Biomedical Engineering, Bahçeşehir Üniversitesi, Istanbul, Turkey
dc.contributor.institutionKadipaşaoǧlu, Kâmuran A., Department of Biomedical Engineering, Bahçeşehir Üniversitesi, Istanbul, Turkey
dc.date.accessioned2025-10-05T16:40:04Z
dc.date.issued2013
dc.description.abstractVirtual design characteristics and performance of the first Turkish axial-flow left ventricular assist device (LVAD) are presented, with emphasis on rotor geometry. The patented rotor design includes a central flow channel carved inside the main block, which carries permanent magnets. A concentric rotor-stator gap minimizes the distance between respective magnets, improving electromagnetic efficiency and creating a second blood pathway. Dual sets of three helical blades, placed on the shaft and external surface of the rotor block, ensure unidirectionality. Hemodynamic performance was tested with computational fluid dynamics (CFD), and rotor-blade geometry was optimized, to maximize overall efficiency d and minimize backflow and wall shear stresses. For a shaft radius of 4.5 mm, rotor blade height of 2.5 mm, and blade inlet and exit metal angles of 67 and 32, pump operation at the nominal head-flow combination (5L/min and 100.4 mm Hg) was achieved at a rotor speed of 10,313rpm. At the nominal point, backflow as percent of total flow was 7.29 and 29.87% at rotor inlet and exit, respectively, overall hydraulic efficiency reached 21.59%, and maximum area-averaged shroud shear was 520 Pa. Overall efficiency peaked at 24.07% for a pump flow of 6.90L/min, and averaged at 22.57% within the flow range of 4-8L/min. We concluded that the design satisfies initial rotor design criteria, and that continued studies with diffuser optimization and transient flow analysis are warranted. Copyright © 2013 by the American Society for Artificial Internal Organs. © 2013 Elsevier B.V., All rights reserved., MEDLINE® is the source for the MeSH terms of this document.
dc.identifier.doi10.1097/MAT.0b013e31828a6bc1
dc.identifier.endpage239
dc.identifier.issn1538943X
dc.identifier.issn10582916
dc.identifier.issue3
dc.identifier.pubmed23644609
dc.identifier.scopus2-s2.0-84877759670
dc.identifier.startpage230
dc.identifier.urihttps://doi.org/10.1097/MAT.0b013e31828a6bc1
dc.identifier.urihttps://hdl.handle.net/20.500.14719/13208
dc.identifier.volume59
dc.language.isoen
dc.relation.oastatusAll Open Access
dc.relation.oastatusBronze Open Access
dc.relation.sourceASAIO Journal
dc.subject.authorkeywordsAxial-flow Heart Pump
dc.subject.authorkeywordsComputational Fluid Dynamics
dc.subject.authorkeywordsDrag Coefficient
dc.subject.authorkeywordsHydraulic Efficiency
dc.subject.authorkeywordsIncidence
dc.subject.authorkeywordsLeft Ventricular Assist Device
dc.subject.authorkeywordsMagnet Cylinder
dc.subject.authorkeywordsSecondary Flow Pathway
dc.subject.authorkeywordsTurbomachinery Electro-magnetic Efficiency
dc.subject.authorkeywordsVelocity Triangle
dc.subject.authorkeywordsExternal Surfaces
dc.subject.authorkeywordsHeart Pump
dc.subject.authorkeywordsHydraulic Efficiency
dc.subject.authorkeywordsIncidence
dc.subject.authorkeywordsLeft Ventricular Assist Device (lvad)
dc.subject.authorkeywordsOverall Efficiency
dc.subject.authorkeywordsVelocity Triangles
dc.subject.authorkeywordsWall Shear Stress
dc.subject.authorkeywordsComputational Fluid Dynamics
dc.subject.authorkeywordsDesign
dc.subject.authorkeywordsDrag Coefficient
dc.subject.authorkeywordsEfficiency
dc.subject.authorkeywordsInlet Flow
dc.subject.authorkeywordsMagnets
dc.subject.authorkeywordsMercury (metal)
dc.subject.authorkeywordsOptimization
dc.subject.authorkeywordsPumps
dc.subject.authorkeywordsShear Flow
dc.subject.authorkeywordsLeft Ventricular Assist Devices
dc.subject.authorkeywordsArticle
dc.subject.authorkeywordsComputational Fluid Dynamics
dc.subject.authorkeywordsElectromagnetic Field
dc.subject.authorkeywordsFlow
dc.subject.authorkeywordsGeometry
dc.subject.authorkeywordsHeart Hemodynamics
dc.subject.authorkeywordsMagnet
dc.subject.authorkeywordsPerformance
dc.subject.authorkeywordsProductivity
dc.subject.authorkeywordsShear Stress
dc.subject.authorkeywordsSurface Property
dc.subject.authorkeywordsVelocity
dc.subject.authorkeywordsVentricular Assist Device
dc.subject.authorkeywordsComputer Simulation
dc.subject.authorkeywordsEquipment Design
dc.subject.authorkeywordsHeart-assist Devices
dc.subject.authorkeywordsHemodynamics
dc.subject.authorkeywordsHumans
dc.subject.authorkeywordsHydrodynamics
dc.subject.indexkeywordsExternal surfaces
dc.subject.indexkeywordsHeart pump
dc.subject.indexkeywordsHydraulic efficiency
dc.subject.indexkeywordsincidence
dc.subject.indexkeywordsLeft ventricular assist device (LVAD)
dc.subject.indexkeywordsOverall efficiency
dc.subject.indexkeywordsVelocity triangles
dc.subject.indexkeywordsWall shear stress
dc.subject.indexkeywordsComputational fluid dynamics
dc.subject.indexkeywordsDesign
dc.subject.indexkeywordsDrag coefficient
dc.subject.indexkeywordsEfficiency
dc.subject.indexkeywordsInlet flow
dc.subject.indexkeywordsMagnets
dc.subject.indexkeywordsMercury (metal)
dc.subject.indexkeywordsOptimization
dc.subject.indexkeywordsPumps
dc.subject.indexkeywordsShear flow
dc.subject.indexkeywordsLeft ventricular assist devices
dc.subject.indexkeywordsarticle
dc.subject.indexkeywordscomputational fluid dynamics
dc.subject.indexkeywordselectromagnetic field
dc.subject.indexkeywordsflow
dc.subject.indexkeywordsgeometry
dc.subject.indexkeywordsheart hemodynamics
dc.subject.indexkeywordsmagnet
dc.subject.indexkeywordsperformance
dc.subject.indexkeywordsproductivity
dc.subject.indexkeywordsshear stress
dc.subject.indexkeywordssurface property
dc.subject.indexkeywordsvelocity
dc.subject.indexkeywordsventricular assist device
dc.subject.indexkeywordsComputer Simulation
dc.subject.indexkeywordsEquipment Design
dc.subject.indexkeywordsHeart-Assist Devices
dc.subject.indexkeywordsHemodynamics
dc.subject.indexkeywordsHumans
dc.subject.indexkeywordsHydrodynamics
dc.titleDesign and numeric evaluation of a novel axial-flow left ventricular assist device
dc.typeArticle
dcterms.referencesFrazier, Oscar Howard, Prologue: Ventricular assist devices and total artificial hearts: A historical perspective, Cardiology Clinics, 21, 1, pp. 1-13, (2003), Untaroiu, Alexandrina, Computational design and experimental testing of a novel axial flow LVAD, ASAIO Journal, 51, 6, pp. 702-710, (2005), Giersiepen, Martin, Estimation of shear stress-related blood damage in heart valve prostheses - in vitro comparison of 25 aortic valves, International Journal of Artificial Organs, 13, 5, pp. 300-306, (1990), Dixon, S. L., Fluid Mechanics and Thermodynamics of Turbomachinery, (2010), Principles of Turbomachinery, (1995), Brushless Permanent Magnet Motor Design, (1994), Bourque, Kevin, In vivo assessment of a rotary left ventricular assist device-induced artificial pulse in the proximal and distal aorta, Artificial Organs, 30, 8, pp. 638-642, (2006)
dspace.entity.typePublication
local.indexed.atScopus
person.identifier.scopus-author-id57204492366
person.identifier.scopus-author-id7004490486

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