Publication: Design and numeric evaluation of a novel axial-flow left ventricular assist device
| dc.contributor.author | Toptop, Koral | |
| dc.contributor.author | Kadipaşaoǧlu, Kâmuran A. | |
| dc.contributor.institution | Toptop, Koral, Department of Biomedical Engineering, Bahçeşehir Üniversitesi, Istanbul, Turkey | |
| dc.contributor.institution | Kadipaşaoǧlu, Kâmuran A., Department of Biomedical Engineering, Bahçeşehir Üniversitesi, Istanbul, Turkey | |
| dc.date.accessioned | 2025-10-05T16:40:04Z | |
| dc.date.issued | 2013 | |
| dc.description.abstract | Virtual design characteristics and performance of the first Turkish axial-flow left ventricular assist device (LVAD) are presented, with emphasis on rotor geometry. The patented rotor design includes a central flow channel carved inside the main block, which carries permanent magnets. A concentric rotor-stator gap minimizes the distance between respective magnets, improving electromagnetic efficiency and creating a second blood pathway. Dual sets of three helical blades, placed on the shaft and external surface of the rotor block, ensure unidirectionality. Hemodynamic performance was tested with computational fluid dynamics (CFD), and rotor-blade geometry was optimized, to maximize overall efficiency d and minimize backflow and wall shear stresses. For a shaft radius of 4.5 mm, rotor blade height of 2.5 mm, and blade inlet and exit metal angles of 67 and 32, pump operation at the nominal head-flow combination (5L/min and 100.4 mm Hg) was achieved at a rotor speed of 10,313rpm. At the nominal point, backflow as percent of total flow was 7.29 and 29.87% at rotor inlet and exit, respectively, overall hydraulic efficiency reached 21.59%, and maximum area-averaged shroud shear was 520 Pa. Overall efficiency peaked at 24.07% for a pump flow of 6.90L/min, and averaged at 22.57% within the flow range of 4-8L/min. We concluded that the design satisfies initial rotor design criteria, and that continued studies with diffuser optimization and transient flow analysis are warranted. Copyright © 2013 by the American Society for Artificial Internal Organs. © 2013 Elsevier B.V., All rights reserved., MEDLINE® is the source for the MeSH terms of this document. | |
| dc.identifier.doi | 10.1097/MAT.0b013e31828a6bc1 | |
| dc.identifier.endpage | 239 | |
| dc.identifier.issn | 1538943X | |
| dc.identifier.issn | 10582916 | |
| dc.identifier.issue | 3 | |
| dc.identifier.pubmed | 23644609 | |
| dc.identifier.scopus | 2-s2.0-84877759670 | |
| dc.identifier.startpage | 230 | |
| dc.identifier.uri | https://doi.org/10.1097/MAT.0b013e31828a6bc1 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14719/13208 | |
| dc.identifier.volume | 59 | |
| dc.language.iso | en | |
| dc.relation.oastatus | All Open Access | |
| dc.relation.oastatus | Bronze Open Access | |
| dc.relation.source | ASAIO Journal | |
| dc.subject.authorkeywords | Axial-flow Heart Pump | |
| dc.subject.authorkeywords | Computational Fluid Dynamics | |
| dc.subject.authorkeywords | Drag Coefficient | |
| dc.subject.authorkeywords | Hydraulic Efficiency | |
| dc.subject.authorkeywords | Incidence | |
| dc.subject.authorkeywords | Left Ventricular Assist Device | |
| dc.subject.authorkeywords | Magnet Cylinder | |
| dc.subject.authorkeywords | Secondary Flow Pathway | |
| dc.subject.authorkeywords | Turbomachinery Electro-magnetic Efficiency | |
| dc.subject.authorkeywords | Velocity Triangle | |
| dc.subject.authorkeywords | External Surfaces | |
| dc.subject.authorkeywords | Heart Pump | |
| dc.subject.authorkeywords | Hydraulic Efficiency | |
| dc.subject.authorkeywords | Incidence | |
| dc.subject.authorkeywords | Left Ventricular Assist Device (lvad) | |
| dc.subject.authorkeywords | Overall Efficiency | |
| dc.subject.authorkeywords | Velocity Triangles | |
| dc.subject.authorkeywords | Wall Shear Stress | |
| dc.subject.authorkeywords | Computational Fluid Dynamics | |
| dc.subject.authorkeywords | Design | |
| dc.subject.authorkeywords | Drag Coefficient | |
| dc.subject.authorkeywords | Efficiency | |
| dc.subject.authorkeywords | Inlet Flow | |
| dc.subject.authorkeywords | Magnets | |
| dc.subject.authorkeywords | Mercury (metal) | |
| dc.subject.authorkeywords | Optimization | |
| dc.subject.authorkeywords | Pumps | |
| dc.subject.authorkeywords | Shear Flow | |
| dc.subject.authorkeywords | Left Ventricular Assist Devices | |
| dc.subject.authorkeywords | Article | |
| dc.subject.authorkeywords | Computational Fluid Dynamics | |
| dc.subject.authorkeywords | Electromagnetic Field | |
| dc.subject.authorkeywords | Flow | |
| dc.subject.authorkeywords | Geometry | |
| dc.subject.authorkeywords | Heart Hemodynamics | |
| dc.subject.authorkeywords | Magnet | |
| dc.subject.authorkeywords | Performance | |
| dc.subject.authorkeywords | Productivity | |
| dc.subject.authorkeywords | Shear Stress | |
| dc.subject.authorkeywords | Surface Property | |
| dc.subject.authorkeywords | Velocity | |
| dc.subject.authorkeywords | Ventricular Assist Device | |
| dc.subject.authorkeywords | Computer Simulation | |
| dc.subject.authorkeywords | Equipment Design | |
| dc.subject.authorkeywords | Heart-assist Devices | |
| dc.subject.authorkeywords | Hemodynamics | |
| dc.subject.authorkeywords | Humans | |
| dc.subject.authorkeywords | Hydrodynamics | |
| dc.subject.indexkeywords | External surfaces | |
| dc.subject.indexkeywords | Heart pump | |
| dc.subject.indexkeywords | Hydraulic efficiency | |
| dc.subject.indexkeywords | incidence | |
| dc.subject.indexkeywords | Left ventricular assist device (LVAD) | |
| dc.subject.indexkeywords | Overall efficiency | |
| dc.subject.indexkeywords | Velocity triangles | |
| dc.subject.indexkeywords | Wall shear stress | |
| dc.subject.indexkeywords | Computational fluid dynamics | |
| dc.subject.indexkeywords | Design | |
| dc.subject.indexkeywords | Drag coefficient | |
| dc.subject.indexkeywords | Efficiency | |
| dc.subject.indexkeywords | Inlet flow | |
| dc.subject.indexkeywords | Magnets | |
| dc.subject.indexkeywords | Mercury (metal) | |
| dc.subject.indexkeywords | Optimization | |
| dc.subject.indexkeywords | Pumps | |
| dc.subject.indexkeywords | Shear flow | |
| dc.subject.indexkeywords | Left ventricular assist devices | |
| dc.subject.indexkeywords | article | |
| dc.subject.indexkeywords | computational fluid dynamics | |
| dc.subject.indexkeywords | electromagnetic field | |
| dc.subject.indexkeywords | flow | |
| dc.subject.indexkeywords | geometry | |
| dc.subject.indexkeywords | heart hemodynamics | |
| dc.subject.indexkeywords | magnet | |
| dc.subject.indexkeywords | performance | |
| dc.subject.indexkeywords | productivity | |
| dc.subject.indexkeywords | shear stress | |
| dc.subject.indexkeywords | surface property | |
| dc.subject.indexkeywords | velocity | |
| dc.subject.indexkeywords | ventricular assist device | |
| dc.subject.indexkeywords | Computer Simulation | |
| dc.subject.indexkeywords | Equipment Design | |
| dc.subject.indexkeywords | Heart-Assist Devices | |
| dc.subject.indexkeywords | Hemodynamics | |
| dc.subject.indexkeywords | Humans | |
| dc.subject.indexkeywords | Hydrodynamics | |
| dc.title | Design and numeric evaluation of a novel axial-flow left ventricular assist device | |
| dc.type | Article | |
| dcterms.references | Frazier, Oscar Howard, Prologue: Ventricular assist devices and total artificial hearts: A historical perspective, Cardiology Clinics, 21, 1, pp. 1-13, (2003), Untaroiu, Alexandrina, Computational design and experimental testing of a novel axial flow LVAD, ASAIO Journal, 51, 6, pp. 702-710, (2005), Giersiepen, Martin, Estimation of shear stress-related blood damage in heart valve prostheses - in vitro comparison of 25 aortic valves, International Journal of Artificial Organs, 13, 5, pp. 300-306, (1990), Dixon, S. L., Fluid Mechanics and Thermodynamics of Turbomachinery, (2010), Principles of Turbomachinery, (1995), Brushless Permanent Magnet Motor Design, (1994), Bourque, Kevin, In vivo assessment of a rotary left ventricular assist device-induced artificial pulse in the proximal and distal aorta, Artificial Organs, 30, 8, pp. 638-642, (2006) | |
| dspace.entity.type | Publication | |
| local.indexed.at | Scopus | |
| person.identifier.scopus-author-id | 57204492366 | |
| person.identifier.scopus-author-id | 7004490486 |
