Publication:
Bisphenol derivatives in cord blood and association between thyroid hormones and potential exposure sources

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dc.contributor.authorBuke Sahin, Merve
dc.contributor.authorCagan, Murat
dc.contributor.authorYi̇Rün, Anıl
dc.contributor.authorÖzyurt, Aylin Balcı
dc.contributor.authorErdemli̇-Köse, Selinay Başak
dc.contributor.authorIyigun, Irem
dc.contributor.authorÇelik, Melda Ozkan
dc.contributor.authorÖzyüncü, Özgür
dc.contributor.authorErkekoǧlu, Pínar
dc.contributor.authorYavuz, Cavit Işïk
dc.contributor.institutionBuke Sahin, Merve, Department of Public Health, Hacettepe Üniversitesi, Ankara, Turkey
dc.contributor.institutionCagan, Murat, Department of Obstetrics and Gynecology, Hacettepe Üniversitesi, Ankara, Turkey
dc.contributor.institutionYi̇Rün, Anıl, Department of Pharmacology and Toxicology, Hacettepe Üniversitesi, Ankara, Turkey
dc.contributor.institutionÖzyurt, Aylin Balcı, Department of Pharmacology and Toxicology, Hacettepe Üniversitesi, Ankara, Turkey, Department of Pharmacology and Toxicology, Bahçeşehir Üniversitesi, Istanbul, Turkey
dc.contributor.institutionErdemli̇-Köse, Selinay Başak, Department of Pharmacology and Toxicology, Hacettepe Üniversitesi, Ankara, Turkey
dc.contributor.institutionIyigun, Irem, Hacettepe Üniversitesi, Ankara, Turkey
dc.contributor.institutionÇelik, Melda Ozkan, Hacettepe Üniversitesi, Ankara, Turkey
dc.contributor.institutionÖzyüncü, Özgür, Department of Obstetrics and Gynecology, Hacettepe Üniversitesi, Ankara, Turkey
dc.contributor.institutionErkekoǧlu, Pínar, Department of Pharmacology and Toxicology, Hacettepe Üniversitesi, Ankara, Turkey
dc.contributor.institutionYavuz, Cavit Işïk, Department of Public Health, Hacettepe Üniversitesi, Ankara, Turkey
dc.date.accessioned2025-10-05T14:56:34Z
dc.date.issued2024
dc.description.abstractEndocrine-disrupting environmental chemicals are a public health concern, particularly fetal exposure to Bisphenol derivatives. This study aimed to assess fetal exposure to Bisphenol derivatives (BPA, BPF, and BPS) by measuring their levels in cord blood and investigating their association with plastic material used in daily life as well as cord blood TSH and free L-thyroxine (fT<inf>4</inf>) levels. In this descriptive study, a questionnaire with a face-to-face interview was administered before birth, and cord blood samples were taken immediately after delivery. The mean levels of BPA, BPF, TSH, and fT<inf>4</inf> were measured as 10.69 ± 2.39 ng/ml, 3.80 ± 0.58 ng/ml, 2.36 ± 0.23 µIU/ml, and 14.18 ± 0.53 pg/ml, respectively, in a total of 104 cord blood samples. All BPS levels remained below the detection limit. Linear regression analysis revealed a positive association between birth weight and cord blood BPA concentration (β = 0.26, p = 0.02). Further research on maternal exposure during the fetal and neonatal period is critical for public health. © 2024 Elsevier B.V., All rights reserved.
dc.identifier.doi10.1080/09603123.2023.2286016
dc.identifier.endpage3045
dc.identifier.issn09603123
dc.identifier.issn13691619
dc.identifier.issue8
dc.identifier.pubmed38007699
dc.identifier.scopus2-s2.0-85178267210
dc.identifier.startpage3036
dc.identifier.urihttps://doi.org/10.1080/09603123.2023.2286016
dc.identifier.urihttps://hdl.handle.net/20.500.14719/7655
dc.identifier.volume34
dc.language.isoen
dc.publisherTaylor and Francis Ltd.
dc.relation.sourceInternational Journal of Environmental Health Research
dc.subject.authorkeywordsBisphenols
dc.subject.authorkeywordsEndocrine Disruptors
dc.subject.authorkeywordsThyroid Hormone
dc.subject.authorkeywords4,4' Isopropylidenediphenol
dc.subject.authorkeywordsLevothyroxine
dc.subject.authorkeywordsPolycarbonate
dc.subject.authorkeywordsThyrotropin
dc.subject.authorkeywordsSulfone
dc.subject.authorkeywordsThyroxine
dc.subject.authorkeywordsBenzhydryl Compounds
dc.subject.authorkeywordsBisphenol A
dc.subject.authorkeywordsBisphenol F
dc.subject.authorkeywordsEndocrine Disruptors
dc.subject.authorkeywordsEnvironmental Pollutants
dc.subject.authorkeywordsPhenols
dc.subject.authorkeywordsSulfones
dc.subject.authorkeywordsThyroid Hormones
dc.subject.authorkeywordsThyrotropin
dc.subject.authorkeywordsThyroxine
dc.subject.authorkeywords4,4' Isopropylidenediphenol
dc.subject.authorkeywordsBisphenol F
dc.subject.authorkeywordsBisphenol S
dc.subject.authorkeywordsEndocrine Disruptor
dc.subject.authorkeywordsLevothyroxine
dc.subject.authorkeywordsPolycarbonate
dc.subject.authorkeywordsThyroid Hormone
dc.subject.authorkeywordsThyrotropin
dc.subject.authorkeywordsUnclassified Drug
dc.subject.authorkeywordsBenzhydryl Derivative
dc.subject.authorkeywordsBisphenol F
dc.subject.authorkeywordsPhenol Derivative
dc.subject.authorkeywordsSulfone
dc.subject.authorkeywordsThyroxine
dc.subject.authorkeywordsBlood
dc.subject.authorkeywordsChemical Compound
dc.subject.authorkeywordsHormone
dc.subject.authorkeywordsMaternal Health
dc.subject.authorkeywordsPlastic
dc.subject.authorkeywordsPollution Exposure
dc.subject.authorkeywordsPublic Health
dc.subject.authorkeywordsRegression Analysis
dc.subject.authorkeywordsAdult
dc.subject.authorkeywordsArticle
dc.subject.authorkeywordsBirth Weight
dc.subject.authorkeywordsCorrelation Analysis
dc.subject.authorkeywordsEducational Status
dc.subject.authorkeywordsFemale
dc.subject.authorkeywordsFetus
dc.subject.authorkeywordsHead Circumference
dc.subject.authorkeywordsHuman
dc.subject.authorkeywordsHuman Tissue
dc.subject.authorkeywordsLimit Of Detection
dc.subject.authorkeywordsLimit Of Quantitation
dc.subject.authorkeywordsLinear Regression Analysis
dc.subject.authorkeywordsMaternal Exposure
dc.subject.authorkeywordsNewborn Period
dc.subject.authorkeywordsObstetric Delivery
dc.subject.authorkeywordsPrenatal Exposure
dc.subject.authorkeywordsQuestionnaire
dc.subject.authorkeywordsUmbilical Cord Blood
dc.subject.authorkeywordsAdverse Event
dc.subject.authorkeywordsChemistry
dc.subject.authorkeywordsFetus Blood
dc.subject.authorkeywordsMale
dc.subject.authorkeywordsNewborn
dc.subject.authorkeywordsPollutant
dc.subject.authorkeywordsPregnancy
dc.subject.authorkeywordsYoung Adult
dc.subject.authorkeywordsAdult
dc.subject.authorkeywordsBenzhydryl Compounds
dc.subject.authorkeywordsEndocrine Disruptors
dc.subject.authorkeywordsEnvironmental Pollutants
dc.subject.authorkeywordsFemale
dc.subject.authorkeywordsFetal Blood
dc.subject.authorkeywordsHumans
dc.subject.authorkeywordsInfant, Newborn
dc.subject.authorkeywordsMale
dc.subject.authorkeywordsMaternal Exposure
dc.subject.authorkeywordsPhenols
dc.subject.authorkeywordsPregnancy
dc.subject.authorkeywordsSulfones
dc.subject.authorkeywordsThyroid Hormones
dc.subject.authorkeywordsThyrotropin
dc.subject.authorkeywordsThyroxine
dc.subject.authorkeywordsYoung Adult
dc.subject.indexkeywords4,4' isopropylidenediphenol
dc.subject.indexkeywordsbisphenol f
dc.subject.indexkeywordsbisphenol s
dc.subject.indexkeywordsendocrine disruptor
dc.subject.indexkeywordslevothyroxine
dc.subject.indexkeywordspolycarbonate
dc.subject.indexkeywordsthyroid hormone
dc.subject.indexkeywordsthyrotropin
dc.subject.indexkeywordsunclassified drug
dc.subject.indexkeywordsbenzhydryl derivative
dc.subject.indexkeywordsbisphenol F
dc.subject.indexkeywordsphenol derivative
dc.subject.indexkeywordssulfone
dc.subject.indexkeywordsthyroxine
dc.subject.indexkeywordsblood
dc.subject.indexkeywordschemical compound
dc.subject.indexkeywordshormone
dc.subject.indexkeywordsmaternal health
dc.subject.indexkeywordsplastic
dc.subject.indexkeywordspollution exposure
dc.subject.indexkeywordspublic health
dc.subject.indexkeywordsregression analysis
dc.subject.indexkeywordsadult
dc.subject.indexkeywordsArticle
dc.subject.indexkeywordsbirth weight
dc.subject.indexkeywordscorrelation analysis
dc.subject.indexkeywordseducational status
dc.subject.indexkeywordsfemale
dc.subject.indexkeywordsfetus
dc.subject.indexkeywordshead circumference
dc.subject.indexkeywordshuman
dc.subject.indexkeywordshuman tissue
dc.subject.indexkeywordslimit of detection
dc.subject.indexkeywordslimit of quantitation
dc.subject.indexkeywordslinear regression analysis
dc.subject.indexkeywordsmaternal exposure
dc.subject.indexkeywordsnewborn period
dc.subject.indexkeywordsobstetric delivery
dc.subject.indexkeywordsprenatal exposure
dc.subject.indexkeywordsquestionnaire
dc.subject.indexkeywordsumbilical cord blood
dc.subject.indexkeywordsadverse event
dc.subject.indexkeywordschemistry
dc.subject.indexkeywordsfetus blood
dc.subject.indexkeywordsmale
dc.subject.indexkeywordsnewborn
dc.subject.indexkeywordspollutant
dc.subject.indexkeywordspregnancy
dc.subject.indexkeywordsyoung adult
dc.subject.indexkeywordsAdult
dc.subject.indexkeywordsBenzhydryl Compounds
dc.subject.indexkeywordsEndocrine Disruptors
dc.subject.indexkeywordsEnvironmental Pollutants
dc.subject.indexkeywordsFemale
dc.subject.indexkeywordsFetal Blood
dc.subject.indexkeywordsHumans
dc.subject.indexkeywordsInfant, Newborn
dc.subject.indexkeywordsMale
dc.subject.indexkeywordsMaternal Exposure
dc.subject.indexkeywordsPhenols
dc.subject.indexkeywordsPregnancy
dc.subject.indexkeywordsSulfones
dc.subject.indexkeywordsThyroid Hormones
dc.subject.indexkeywordsThyrotropin
dc.subject.indexkeywordsThyroxine
dc.subject.indexkeywordsYoung Adult
dc.titleBisphenol derivatives in cord blood and association between thyroid hormones and potential exposure sources
dc.typeArticle
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dspace.entity.typePublication
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