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Posterior fossa astroblastoma in a child: a case report and a review of the literature

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dc.contributor.authorKurtkaya-Yapicier, Özlem Sahan
dc.contributor.authorDemir, Mustafa Kemal
dc.contributor.authorOzdamarlar, Umut
dc.contributor.authorKilic, Deniz
dc.contributor.authorAkakin, Akin In
dc.contributor.authorKilic, Turker D.
dc.contributor.institutionKurtkaya-Yapicier, Özlem Sahan, Department of Pathology, Bahçeşehir Üniversitesi, Istanbul, Turkey
dc.contributor.institutionDemir, Mustafa Kemal, Department of Radiology, Bahçeşehir Üniversitesi, Istanbul, Turkey
dc.contributor.institutionOzdamarlar, Umut, Department of Radiology, Bahçeşehir Üniversitesi, Istanbul, Turkey
dc.contributor.institutionKilic, Deniz, Bahçeşehir Üniversitesi, Istanbul, Turkey
dc.contributor.institutionAkakin, Akin In, Department of Neurosurgery, Bahçeşehir Üniversitesi, Istanbul, Turkey
dc.contributor.institutionKilic, Turker D., Department of Neurosurgery, Bahçeşehir Üniversitesi, Istanbul, Turkey
dc.date.accessioned2025-10-05T15:57:59Z
dc.date.issued2019
dc.description.abstractA 4-year-old girl presented to the hospital with a progressive headache, difficulty walking, and persistent daily vomiting for 3 weeks. Papilledema was observed on fundoscopic examination. A large left cerebellovermian tumor with bubbly appearance was discovered. Total removal of the tumor mass was performed, and a diagnosis of low-grade astroblastoma was made. Adjuvant radiotherapy was performed due to the risk of recurrence. The patient is disease-free and has been kept on close follow-up for 6 months. The occurrence of posterior fossa astroblastoma has been rarely reported in the literature. Thus, when a bubby appearance enhancing cystic solid tumor is located on the cerebellar hemisphere in a child, an astroblastoma should also be included in the differential diagnosis. © 2019 Elsevier B.V., All rights reserved.
dc.identifier.doi10.1007/s00381-019-04113-3
dc.identifier.endpage1255
dc.identifier.issn14330350
dc.identifier.issn02567040
dc.identifier.issue7
dc.identifier.pubmed30859299
dc.identifier.scopus2-s2.0-85068459803
dc.identifier.startpage1251
dc.identifier.urihttps://doi.org/10.1007/s00381-019-04113-3
dc.identifier.urihttps://hdl.handle.net/20.500.14719/11050
dc.identifier.volume35
dc.language.isoen
dc.publisherSpringer Verlag service@springer.de
dc.relation.sourceChild's Nervous System
dc.subject.authorkeywordsAstroblastoma
dc.subject.authorkeywordsCerebellum
dc.subject.authorkeywordsDiagnosis
dc.subject.authorkeywordsPediatric
dc.subject.authorkeywordsEpithelial Membrane Antigen
dc.subject.authorkeywordsGlial Fibrillary Acidic Protein
dc.subject.authorkeywordsIni1 Protein
dc.subject.authorkeywordsKi 67 Antigen
dc.subject.authorkeywordsOligodendrocyte Transcription Factor 2
dc.subject.authorkeywordsPeptides And Proteins
dc.subject.authorkeywordsTumor Marker
dc.subject.authorkeywordsUnclassified Drug
dc.subject.authorkeywordsVimentin
dc.subject.authorkeywordsAdjuvant Radiotherapy
dc.subject.authorkeywordsArticle
dc.subject.authorkeywordsAstroblastoma
dc.subject.authorkeywordsBrain Edema
dc.subject.authorkeywordsCancer Grading
dc.subject.authorkeywordsCancer Morphology
dc.subject.authorkeywordsCancer Patient
dc.subject.authorkeywordsCancer Surgery
dc.subject.authorkeywordsCase Report
dc.subject.authorkeywordsChild
dc.subject.authorkeywordsClinical Article
dc.subject.authorkeywordsCraniotomy
dc.subject.authorkeywordsFemale
dc.subject.authorkeywordsFollow Up
dc.subject.authorkeywordsGlioma
dc.subject.authorkeywordsHeadache
dc.subject.authorkeywordsHistopathology
dc.subject.authorkeywordsHuman
dc.subject.authorkeywordsHuman Tissue
dc.subject.authorkeywordsImmunohistochemistry
dc.subject.authorkeywordsKarnofsky Performance Status
dc.subject.authorkeywordsLabeling Index
dc.subject.authorkeywordsNeuroimaging
dc.subject.authorkeywordsNuclear Magnetic Resonance Imaging
dc.subject.authorkeywordsOphthalmoscopy
dc.subject.authorkeywordsPapilledema
dc.subject.authorkeywordsPosterior Cranial Fossa Tumor
dc.subject.authorkeywordsPosterior Fossa
dc.subject.authorkeywordsPreschool Child
dc.subject.authorkeywordsPriority Journal
dc.subject.authorkeywordsRecurrence Risk
dc.subject.authorkeywordsTumor Volume
dc.subject.authorkeywordsVomiting
dc.subject.authorkeywordsWalking Difficulty
dc.subject.authorkeywordsCerebellum Tumor
dc.subject.authorkeywordsDiagnostic Imaging
dc.subject.authorkeywordsDifferential Diagnosis
dc.subject.authorkeywordsNeuroepithelioma
dc.subject.authorkeywordsTreatment Outcome
dc.subject.authorkeywordsChild, Preschool
dc.subject.authorkeywordsDiagnosis, Differential
dc.subject.authorkeywordsFemale
dc.subject.authorkeywordsHumans
dc.subject.authorkeywordsInfratentorial Neoplasms
dc.subject.authorkeywordsMagnetic Resonance Imaging
dc.subject.authorkeywordsNeoplasms, Neuroepithelial
dc.subject.authorkeywordsTreatment Outcome
dc.subject.indexkeywordsepithelial membrane antigen
dc.subject.indexkeywordsglial fibrillary acidic protein
dc.subject.indexkeywordsini1 protein
dc.subject.indexkeywordsKi 67 antigen
dc.subject.indexkeywordsoligodendrocyte transcription factor 2
dc.subject.indexkeywordspeptides and proteins
dc.subject.indexkeywordstumor marker
dc.subject.indexkeywordsunclassified drug
dc.subject.indexkeywordsvimentin
dc.subject.indexkeywordsadjuvant radiotherapy
dc.subject.indexkeywordsArticle
dc.subject.indexkeywordsastroblastoma
dc.subject.indexkeywordsbrain edema
dc.subject.indexkeywordscancer grading
dc.subject.indexkeywordscancer morphology
dc.subject.indexkeywordscancer patient
dc.subject.indexkeywordscancer surgery
dc.subject.indexkeywordscase report
dc.subject.indexkeywordschild
dc.subject.indexkeywordsclinical article
dc.subject.indexkeywordscraniotomy
dc.subject.indexkeywordsfemale
dc.subject.indexkeywordsfollow up
dc.subject.indexkeywordsglioma
dc.subject.indexkeywordsheadache
dc.subject.indexkeywordshistopathology
dc.subject.indexkeywordshuman
dc.subject.indexkeywordshuman tissue
dc.subject.indexkeywordsimmunohistochemistry
dc.subject.indexkeywordsKarnofsky Performance Status
dc.subject.indexkeywordslabeling index
dc.subject.indexkeywordsneuroimaging
dc.subject.indexkeywordsnuclear magnetic resonance imaging
dc.subject.indexkeywordsophthalmoscopy
dc.subject.indexkeywordspapilledema
dc.subject.indexkeywordsposterior cranial fossa tumor
dc.subject.indexkeywordsposterior fossa
dc.subject.indexkeywordspreschool child
dc.subject.indexkeywordspriority journal
dc.subject.indexkeywordsrecurrence risk
dc.subject.indexkeywordstumor volume
dc.subject.indexkeywordsvomiting
dc.subject.indexkeywordswalking difficulty
dc.subject.indexkeywordscerebellum tumor
dc.subject.indexkeywordsdiagnostic imaging
dc.subject.indexkeywordsdifferential diagnosis
dc.subject.indexkeywordsneuroepithelioma
dc.subject.indexkeywordstreatment outcome
dc.subject.indexkeywordsChild, Preschool
dc.subject.indexkeywordsDiagnosis, Differential
dc.subject.indexkeywordsFemale
dc.subject.indexkeywordsHumans
dc.subject.indexkeywordsInfratentorial Neoplasms
dc.subject.indexkeywordsMagnetic Resonance Imaging
dc.subject.indexkeywordsNeoplasms, Neuroepithelial
dc.subject.indexkeywordsTreatment Outcome
dc.titlePosterior fossa astroblastoma in a child: a case report and a review of the literature
dc.typeArticle
dcterms.referencesPizer, Barry L., Congenital astroblastoma: An immunohistochemical study. Case report, Journal of Neurosurgery, 83, 3, pp. 550-555, (1995), Bahadur, Gulam H., Age definitions, childhood and adolescent cancers in relation to reproductive issues [1], Human Reproduction, 15, 1, (2000), Sughrue, Michael Edward, Clinical features and post-surgical outcome of patients with astroblastoma, Journal of Clinical Neuroscience, 18, 6, pp. 750-754, (2011), A Classification of the Tumors of the Glioma Group on A Histogenetic Basis with A Correlated Study of Prognosis, (1926), Bailev, Percival, ASTROBLASTOMAS OF THE BRAIN, Acta Psychiatrica Scandinavica, 5, 3, pp. 439-461, (1930), Grotts, Bruce F., Astroblastoma of the cerebellum in an infant, report of a case, Archives of pediatrics, 66, 7, pp. 283-288, (1949), Ahmed, Kamran A., Astroblastomas: A Surveillance, Epidemiology, and End Results (SEER)-Based Patterns of Care Analysis, World Neurosurgery, 82, 1-2, pp. e291-e297, (2014), Bell, John W., Neuroradiologic characteristics of astroblastoma, Neuroradiology, 49, 3, pp. 203-209, (2007), Hammas, Nawal, Astroblastoma - A rare and challenging tumor: A case report and review of the literature, Journal of Medical Case Reports, 12, 1, (2018), Cunningham, Danielle A., Neuroradiologic characteristics of astroblastoma and systematic review of the literature: 2 new cases and 125 cases reported in 59 publications, Pediatric Radiology, 46, 9, pp. 1301-1308, (2016)
dspace.entity.typePublication
local.indexed.atScopus
person.identifier.scopus-author-id6602188985
person.identifier.scopus-author-id56559523000
person.identifier.scopus-author-id57186669300
person.identifier.scopus-author-id57753819000
person.identifier.scopus-author-id14830248000
person.identifier.scopus-author-id55042518500

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