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Parathyroidectomy Results in Primary Hyperparathyroidism:Analysis of the Results From a Single Center

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dc.contributor.authorYetkin, Gürkan
dc.contributor.authorAygün, Nurcihan
dc.contributor.authorUludağ, Mehmet
dc.contributor.authorİşgör, Adnan
dc.contributor.authorAkgün, İsmail Ethem
dc.contributor.authorÜnlü, Mehmet Taner
dc.contributor.authorErol, Rümeysa Selvinaz
dc.contributor.institutionSAĞLIK BİLİMLERİ ÜNİVERSİTESİ
dc.contributor.institutionSAĞLIK BİLİMLERİ ÜNİVERSİTESİ
dc.contributor.institutionSAĞLIK BİLİMLERİ ÜNİVERSİTESİ
dc.contributor.institutionBAHÇEŞEHİR ÜNİVERSİTESİ
dc.contributor.institutionSAĞLIK BİLİMLERİ ÜNİVERSİTESİ
dc.contributor.institutionT.C. SAĞLIK BAKANLIĞI
dc.contributor.institutionSAĞLIK BİLİMLERİ ÜNİVERSİTESİ
dc.date.accessioned2025-09-20T19:57:50Z
dc.date.issued2021
dc.date.submitted28.01.2022
dc.description.abstractObjectives: The curative treatment of primary hyperparathyroidism (PHPT) is surgery. Persistent and recurrent disease may de velop after surgical treatment. In this study, we aimed to evaluate the surgical cure rate in patients who underwent surgery forPHPT in our clinic. Methods: The data of patients who underwent parathyroidectomy for PHPT by two experienced surgeons between 2000 and2015 in our clinic were retrospectively evaluated. Patients who were followed for at least 6 months after their first parathyroidec tomy were included in the study. Surgical cure and persistent and recurrent disease rates were evaluated in patients. Results: During this period, 368 interventions were performed in 357 patients (293 F and 64 M) who were operated for PHPT inour clinic, with a mean age of 54.9±13.1 years. In the first surgery, 116 patients (32.5%) had bilateral neck exploration, 251 patients(67.5%) had unilateral neck exploration (UNE) or focused parathyroid surgery (FPS). In the first operation, 343 patients (96.1%) hadcure, 14 patients (13 F and 1 M) remained persistent. Secondary surgical intervention was performed in 11 patients. UNE or FPS wasperformed to 10 patients (90.9%), partial sternotomy was performed to one patient. Ten of the patients had cure. Three of these pa tients had a solitary parathyroid adenoma that was not removed in the first surgery, and seven patients had a second adenoma. Fourpatients remained persistent (1.1%). Recurrent disease developed in four patients during follow-up (1.1%). Total cure rate was 97.8%. Conclusion: The only definitive treatment for PHPT is surgery. High surgical cure can be achieved by pre-operative evaluationand appropriate surgical planning. However, persistent PHPT may develop, especially due to double adenoma or ectopic location.Patients with persistent PHPT can be evaluated with repeat imaging methods and with appropriate surgical planning, a high curerate can be obtained in secondary surgery, which can increase the total surgical cure rate. Recurrence rate is rare.
dc.identifier.doi10.14744/SEMB.2021.72681
dc.identifier.endpage178
dc.identifier.issn1302-7123
dc.identifier.issn1308-5123
dc.identifier.issue2
dc.identifier.startpage173
dc.identifier.urihttps://hdl.handle.net/20.500.14719/4889
dc.identifier.volume55
dc.language.isoen
dc.relation.journalŞişli Etfal Hastanesi Tıp Bülteni
dc.subjectTıbbi Araştırmalar Deneysel
dc.subjectEndokrinoloji ve Metabolizma
dc.subjectGenel ve Dahili Tıp
dc.subjectPatoloji
dc.titleParathyroidectomy Results in Primary Hyperparathyroidism:Analysis of the Results From a Single Center
dc.typeResearch Article
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