Adherence to Anti-hypertensive Treatment in Geriatric Patients: A Systematic Review and Meta-analysis, Geriatrik Hastaların Anti-hipertansif Tedaviye Uyumu: Sistematik Derleme ve Metaanaliz

Abstract

Objective: This study was planned for the systematic review and meta-analysis of the studies evaluating adherence to antihypertensive treatment in geriatric patients. Material and Methods: Google Scholar, Web of Science, PubMed, CINAHL, MEDLINE and Scopus databases were searched using the keywords Geriatric, Geriatric patients, Elderly, Elderly patients, Hypertension, Anti-hypertensive agents, Drug compliance. A total of 13 studies were included in the meta-analysis. The included studies were evaluated with the quality evaluation criteria proposed by Polit and Beck. The agreement between the researchers was measured by the kappa test for agreement. The odds ratio was used for effect sizes, Cochran's Q test was used for heterogeneity, the funnel plot and Kendall's tau coefficient were used for publication bias. Results: Age, gender, educational status, income level, place of residence and presence of comorbid diseases that affect adherence to anti-hypertensive treatment in geriatric patients were examined. The fact that age and presence of comorbid diseases decreased adherence to anti-hypertensive treatment (OR <1) while being a resident of the city, high educational status, and income level increased adherence to anti-hypertensive treatment (OR >1) in geriatric patients was confirmed by the meta-analysis. Conclusion: The factors affecting adherence to anti-hypertensive treatment in geriatric patients were found to be similar to the literature. In contrast to the literature, it was found that gender did not affect adherence to anti-hypertensive treatment in any way. This difference was thought to be due to the lack of homogeneity in the samples of the studies. © 2022 Elsevier B.V., All rights reserved.