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The Association Between Migraine, Metabolic Syndrome, Insulin Resistance, and Obesity in Women: A Case-Control Study

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dc.contributor.authorGür Özmen, Selen
dc.contributor.authorKarahan Özcan, Ruhan
dc.contributor.institutionBahçeşehir Üniversitesi
dc.contributor.institutionTanımlanmamış Kurum
dc.date.accessioned2025-09-20T20:00:10Z
dc.date.issued2019
dc.date.submitted25.06.2020
dc.description.abstractObjectives: The aim of this study was to examine the relationship between migraines and obesity, insulin resistance (IR), andmetabolic syndrome in female migraineurs.Methods: A total of 141 female patients who experience migraines and a control group of 141 sex- and age-matched individualswho do not were enrolled in this case-control study. The migraine group was composed of patients from the Gebze Fatih Community Hospital (Kocaeli, Turkey) neurology outpatient service and the control group included hospital staff and friends who volunteered to participate. Descriptive statistics and multivariate logistic regression analyses were performed. Migraine was designatedas a dependent variable. Family history of migraine, stroke, metabolic syndrome, cardiac disease, hypertension, hyperlipidemia,and diabetes mellitus, cigarette use, alcohol consumption, and the presence of hypertension, IR, hypertriglyceridemia, low level ofhigh-density lipoprotein (HDL), central obesity, metabolic syndrome, as well as homeostasis model assessment and quantitativeinsulin sensitivity check index results were selected as independent variables.Results: The mean waist circumference, mean height, mean weight, and central obesity were greater in the control group (p=0.009,0.004, 0.036, and 0.015, respectively). A multivariate logistic regression model of migraine presence showed that a family history ofmigraine (odds ratio [OR]: 1.542, 95% confidence interval [CI]: 2.451-8.905, p<0.0001), family history of stroke (OR: 1.043, 95% CI: 1.214-6.633, p=0.016), and no central obesity (OR: -0.705, 95% CI: -0.290-0.843, p=0.010) were statistically significant variables in our study.Conclusion: The results of our study indicated that IR and metabolic syndrome were not associated with migraine in women. Therewas an inverse relationship between central obesity and migraine. Additional research with larger participant groups should beperformed to further explore the complex relationship between migraine, obesity, IR, and metabolic syndrome.
dc.identifier.doi10.14744/SEMB.2018.09582
dc.identifier.endpage402
dc.identifier.issn1302-7123
dc.identifier.issn1308-5123
dc.identifier.issue4
dc.identifier.startpage395
dc.identifier.urihttps://hdl.handle.net/20.500.14719/5280
dc.identifier.volume53
dc.language.isoen
dc.relation.journalŞişli Etfal Hastanesi Tıp Bülteni
dc.subjectEndokrinoloji ve Metabolizma
dc.subjectGenel ve Dahili Tıp
dc.subjectNörolojik Bilimler
dc.subjectKalp ve Kalp Damar Sistemi
dc.titleThe Association Between Migraine, Metabolic Syndrome, Insulin Resistance, and Obesity in Women: A Case-Control Study
dc.typeResearch Article
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