Publication: Hemoglobin F ve İlişkili Klinik Durumlar
| dc.contributor.author | Karasu Tezcan, Gülsün | |
| dc.contributor.author | Uygun, Vedat | |
| dc.contributor.institution | Bahçeşehir Üniversitesi | |
| dc.contributor.institution | Bahçeşehir Üniversitesi | |
| dc.date.accessioned | 2025-09-20T20:02:46Z | |
| dc.date.issued | 2016 | |
| dc.date.submitted | 29.07.2022 | |
| dc.description.abstract | Hemoglobin F (HbF), oksijen bağlama yeteneği hemoglobin A (HbA)´dan daha yüksek olması ve bu nedenle anneden fetüse oksijen taşınmasını kolaylaştırması nedeniyle intrauterin dönemin en önemli hemoglobinidir. Erişkinlerde fetal hemoglobin düzeyi yaş, cinsiyet ve bazı kalıtsal özelliklere bağlıdır. Kalıtsal özellikler ? globin gen kümesi ile ilişkili veya ilişkisiz farklı kromozomlardaki bir kaç gen ile bağlantılıdır. Bu derlemede hemoglobin F´nin yüksek kalmasına neden olan herediter persistan fetal hemoglobin ve bazı klinik durumlar ele alınmıştır | |
| dc.identifier.endpage | 234 | |
| dc.identifier.issn | 1300-2694 | |
| dc.identifier.issn | 2587-0351 | |
| dc.identifier.issue | 2 | |
| dc.identifier.startpage | 229 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14719/5704 | |
| dc.identifier.volume | 23 | |
| dc.language.iso | tr | |
| dc.relation.journal | Van Tıp Dergisi | |
| dc.subject | Genel ve Dahili Tıp | |
| dc.subject | Hematoloji | |
| dc.subject | Genetik ve Kalıtım | |
| dc.subject | Fizyoloji | |
| dc.title | Hemoglobin F ve İlişkili Klinik Durumlar | |
| dc.type | Review | |
| dcterms.references | Schechter AN. Hemoglobin research and the origins of molecular medicine. Blood 2008, 112(10): 3927-3938.,Goodman M, Czelusniak J, Koop BF, Tagle DA, Slightom JL. Globins: a case study in molecular phylogeny. Cold Spring Harb Symp Quant Biol 1987, 52: 875-890.,Bain BJ. Haemoglobinopathy diagnosis. Malden, Mass.: Blackwell Pub., 2006.xiii, 314 p.,Mabaera R, Richardson CA, Johnson K, Hsu M, Fiering S, Lowrey CH. Developmental- and differentiation-specific patterns of human gamma- and beta-globin promoter DNA methylation. Blood 2007, 110(4): 1343-1352.,Charache S, Dover G, Smith K, Talbot CC, Jr., Moyer M, Boyer S. Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta-globin gene complex. Proc Natl Acad Sci U S A 1983, 80(15): 4842-4846.,Garner C, Tatu T, Reittie JE, Littlewood T, Darley J, Cervino S, et al. Genetic influences on F cells and other hematologic variables: a twin heritability study. Blood 2000, 95(1): 342-346.,Jane SM, Cunningham JM. Understanding fetal globin gene expression: a step towards effective HbF reactivation in haemoglobinopathies. Br J Haematol 1998, 102(2): 415-422.,Eridani S, Mosca A. Fetal hemoglobin reactivation and cell engineering in the treatment of sickle cell anemia. J Blood Med 2011, 2: 23-30.,Thein SL, Menzel S. Discovering the genetics underlying foetal haemoglobin production in adults. Br J Haematol 2009, 145(4): 455-467.,Mosca A, Paleari R, Leone D, Ivaldi G. The relevance of hemoglobin F measurement in the diagnosis of thalassemias and related hemoglobinopathies. Clin Biochem 2009, 42(18): 1797-1801.,Rohlfing CL, Connolly SM, England JD, Hanson SE, Moellering CM, Bachelder JR, et al. The effect of elevated fetal hemoglobin on hemoglobin A1c results: five common hemoglobin A1c methods compared with the IFCC reference method. Am J Clin Pathol 2008, 129(5): 811-814.,Hoyer JD, Penz CS, Fairbanks VF, Hanson CA, Katzmann JA. Flow cytometric measurement of hemoglobin F in RBCs: diagnostic usefulness in the distinction of hereditary persistence of fetal hemoglobin (HPFH) and hemoglobin S-hPFH from other conditions with elevated levels of hemoglobin F. Am J Clin Pathol 2002, 117(6): 857-863.,Craig JE, Rochette J, Sampietro M, Wilkie AO, Barnetson R, Hatton CS, et al. Genetic heterogeneity in heterocellular hereditary persistence of fetal hemoglobin. Blood 1997, 90(1): 428-434.,Miyoshi K, Kaneto Y, Kawai H, Ohchi H, Niki S, Hasegawa K, et al. X-linked dominant control of F-cells in normal adult life: characterization of the Swiss type as hereditary persistence of fetal hemoglobin regulated dominantly by gene(s) on X chromosome. Blood 1988, 72(6): 1854-1860.,Paciaroni K, Gallucci C, De Angelis G, Alfieri C, Roveda A, Lucarelli G. Sustained and full fetal hemoglobin production after failure of bone marrow transplant in a patient homozygous for beta 0-thalassemia: a clinical remission despite genetic disease and transplant rejection. Am J Hematol 2009, 84(6): 372-373.,Adekile AD. Limitations of Hb F as a phenotypic modifier in sickle cell disease: study of Kuwaiti Arab patients. Hemoglobin 2011, 35(5-6): 607- 617.,Wood B, Higgs D. Molecular basis of thalassaemia syndromes. Handbook on Disorders of Erythropoiesis, Erythrocytes and Iron Metabolism, 2009. p 260.,Ender KL, Lee MT, Sheth S, Licursi M, Crotty J, Barral S, et al. Fetal hemoglobin levels in African American and Hispanic children with sickle cell disease at baseline and in response to hydroxyurea. J Pediatr Hematol Oncol 2011, 33 (7): 496-499.,Ngo DA, Aygun B, Akinsheye I, Hankins JS, Bhan I, Luo HY, et al. Fetal haemoglobin levels and haematological characteristics of compound heterozygotes for haemoglobin S and deletional hereditary persistence of fetal haemoglobin. Br J Haematol 2012, 156(2): 259-264.,Oberoi S, Das R, Panigrahi I, Kaur J, Marwaha RK. Xmn1-G gamma polymorphism and clinical predictors of severity of disease in beta- thalassemia intermedia. Pediatr Blood Cancer 2011, 57(6): 1025-1028.,Nemati H, Rahimi Z, Bahrami G. The Xmn1 polymorphic site 5' to the (G)gamma gene and its correlation to the (G)gamma:(A)gamma ratio, age at first blood transfusion and clinical features in beta-thalassemia patients from Western Iran. Mol Biol Rep 2010, 37(1): 159-164.,Stamatoyannopoulos G, Veith R, Galanello R, Papayannopoulou T. Hb F production in stressed erythropoiesis: observations and kinetic models. Ann N Y Acad Sci 1985, 445: 188-197.,Testa U. Fetal hemoglobin chemical inducers for treatment of hemoglobinopathies. Ann Hematol 2009, 88(6): 505-528.,Veith R, Galanello R, Papayannopoulou T, Stamatoyannopoulos G. Stimulation of F-cell production in patients with sickle-cell anemia treated with cytarabine or hydroxyurea. N Engl J Med 1985, 313(25): 1571-1575.,Meier ER, Byrnes C, Weissman M, Noel P, Luban NL, Miller JL. Expression patterns of fetal hemoglobin in sickle cell erythrocytes are both patient- and treatment-specific during childhood. Pediatr Blood Cancer 2011, 56(1): 103-109.,Little JA, McGowan VR, Kato GJ, Partovi KS, Feld JJ, Maric I, et al. Combination erythropoietin-hydroxyurea therapy in sickle cell disease: experience from the National Institutes of Health and a literature review. Haematologica 2006, 91(8): 1076-1083.,Mabaera R, Greene MR, Richardson CA, Conine SJ, Kozul CD, Lowrey CH. Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin. Blood 2008, 111(1): 411-420.,Murji A, Sobel ML, Hasan L, McLeod A, Waye JS, Sermer M, et al. Pregnancy outcomes in women with elevated levels of fetal hemoglobin. J Matern Fetal Neonatal Med 2012, 25(2): 125-129.,Bhanu NV, Trice TA, Lee YT, Miller JL. A signaling mechanism for growth-related expression of fetal hemoglobin. Blood 2004, 103(5): 1929-1933.,Savasan S, Sarnaik SA. Persistent elevation of fetal hemoglobin following chemotherapy in sickle cell disease. Pediatr Blood Cancer 2012.,Blau CA, Constantoulakis P, al-Khatti A, Spadaccino E, Goldwasser E, Papayannopoulou T, et al. Fetal hemoglobin in acute and chronic states of erythroid expansion. Blood 1993, 81(1): 227-233. | |
| dspace.entity.type | Publication | |
| local.indexed.at | TRDizin |
Files
Original bundle
1 - 1 of 1
No Thumbnail Available
- Name:
- Hemoglobin F ve İlişkili Klinik Durumlar.pdf
- Size:
- 318.59 KB
- Format:
- Adobe Portable Document Format
