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Analysis of Patients with 1988 FIGO Stage-II Endometrial Cancer

dc.contributor.authorKöse, M. Faruk
dc.contributor.authorTuran, Ahmet Taner
dc.contributor.authorKimyon, Günsu
dc.contributor.authorKaralök, Mustafa Alper
dc.contributor.authorTaşçı, Tolga
dc.contributor.authorBoran, Nurettin
dc.contributor.authorTulunay, Gökhan
dc.contributor.authorÜreyen, Işın
dc.contributor.institutionBahçeşehir Üniversitesi
dc.contributor.institutionT.C. Sağlık Bakanlığı
dc.contributor.institutionT.C. Sağlık Bakanlığı
dc.contributor.institutionT.C. Sağlık Bakanlığı
dc.contributor.institutionT.C. Sağlık Bakanlığı
dc.contributor.institutionT.C. Sağlık Bakanlığı
dc.contributor.institutionT.C. Sağlık Bakanlığı
dc.contributor.institutionT.C. Sağlık Bakanlığı
dc.date.accessioned2025-09-20T20:03:20Z
dc.date.issued2014
dc.date.submitted29.07.2022
dc.description.abstractEvre II endometriyum kanserinin yönetimi hala tartışmalıdır. Kliniğimizde opere olan evre II endometriyum kanseri olan hastaları tedavi çeşitleri, cerrahi-patolojik faktörler, rekürrens şekli ve sıklığı açısından değerlendirdik. Çalışmaya Ocak 1993 ve Ekim 2012 tarihleri arasında evreleme cerrahisi geçiren evre II endometriyum kanseri olan 53 hasta dahil edildi. Hastaların ortalama yaşı 57 idi. Servikal invazyon 47 hastanın (%88.7) preoperatif incelemesinde saptanamadı. Otuz-sekiz hastaya basit histerektomi (BH) ve 15 hastaya radikal histerektomi (RH) yapıldı. Tüm hastalara pelvik ve paraaortik lenfadenektomi yapıldı. Kırk-iki hasta adjuvan radyoterapi aldı. Hastaların ortalama takip süresi 39 aydı (aralık, 1-139). Rekürrens 4 hastada gelişti. RH ve BH grupları arasında rekürrens açısından farklılık yoktu (p= 0.53). İleri yaş, derin myometrial invazyon ve az sayıda lenf nodu çıkartılması rekürrens ile ilişkiliydi. Evre II endometriyum kanserinde radikal cerrahilere ve farklı adjuvan radyoterapi protokollerine rağmen rekürrenslerin ve mortalitenin esas sorumlusu uzak metastazlardır. Bundan dolayı, uzak metastazları engelleyebilmek için sistemik adjuvan tedavi bu hastalığın birinci basamak tedavisinde düşünülebilir.
dc.identifier.endpage246
dc.identifier.issn1306-133X
dc.identifier.issue4
dc.identifier.startpage239
dc.identifier.urihttps://hdl.handle.net/20.500.14719/5806
dc.identifier.volume24
dc.language.isotr
dc.relation.journalUluslararası Hematoloji-Onkoloji Dergisi
dc.subjectOnkoloji
dc.titleAnalysis of Patients with 1988 FIGO Stage-II Endometrial Cancer
dc.typeResearch Article
dcterms.referencesEser SY and Karakılınç H. Cancer Incidence in Turkey. Chapter 1.6 page: 35-51, In: Cancer Control in Turkey. Tuncer AM, Özgül N, Olcayto E and Gültekin M (eds). Ministry Publication Number: 776, Ankara, 2010.,Creasman WT, Odicino F, Maisonneuve P, et al. Carcinoma of the corpus uteri. FIGO 26th Annual Report on the Results of Treatment in Gynecological Cancer. Int J Gynaecol Obstet 95 Suppl 1:S105-43, 2006.,Benedet JL, Bender H, Jones 3rd H, et al. FIGO staging classifications and clinical practice guidelines in the management of gynecologic cancers. FIGO Committee on Gynecologic Oncology. Int J Gynaecol Obstet 70: 209-262, 2000.,Creasman W. Revised FIGO staging for carcinoma of the endometrium. Int J Gynaecol Obstet 105: 109, 2009.,Prat J. Prognostic parameters of endometrial carcinoma. Hum Pathol 35: 649-662, 2004.,Heyman J, Reuterwall O, Benner S. The Radiumhemmet experience with radiotherapy in cancer of the corpus of the uterus. Acta Radiol 22: 13-98, 1941.,Kottmeier HL. The classification and clinical staging of carcinoma of the uterus and vagina. J Int Fed Gynaecol 1: 83-93, 1963.,Cornelison TL, Trimble EL, Kosary CL. SEER data, corpus uteri cancer: treatment trends versus survival for FIGO stage II, 1988-1994. Gynecol Oncol 74: 350-355, 1999.,Mariani A, Webb MJ, Keeney GL, et al. Role of wide/radical hysterectomy and pelvic lymph node dissection in endometrial cancer with cervical involvement. Gynecol Oncol 83: 72- 80, 2001.,Eltabbakh GH, Moore AD. Survival of women with surgical stage II endometrial cancer. Gynecol Oncol 74: 80-85, 1999.,Ayhan A, Taskiran C, Celik C, Yuce K. The long-term survival of women with surgical stage II endometrioid type endometrial cancer. Gynecol Oncol 93: 9-13, 2004.,Cohn DE, Woeste EM, Cacchio S, et al. Clinical and pathologic correlates in surgical stage II endometrial carcinoma. Obstet Gynecol 109: 1062-7, 2007.,Boente MP, Edgardo LY, McIntosh DG, et al. Prognostic factors and long-term survival in endometrial adenocarcinoma with cervical involvement. Gynecol Oncol 51: 316-322, 1993.,Leminen A, Forss M, Lehtovirta P. Endometrial adenocarcinoma with clinical evidence of cervical involvement: accuracy of diagnostic procedures, clinical course, and prognostic factors. Acta Obstet Gynecol Scand 74: 61-66, 1995.,Tamura H, Nakai Y, Nagano T, et al. Treatment and prognosis of pT2 endometrial carcinoma. Nihon Sanka Fujinka Gakkai Zasshi 43: 315-320, 1991.,Orezzoli JP, Sioletic S, Olawaiye A, et al. Stage II endometrioid adenocarcinoma of the endometrium: clinical implications of cervical stromal invasion. Gynecol Oncol 113: 316-323, 2009.,Cannon GM, Geye H, Terakedis BE, et al. Outcomes following surgery and adjuvant radiation in stage II endometrial adenocarcinoma. Gynecol Oncol 113: 176-180, 2009.,Pitson G, Colgan T, Levin W, et al. Stage II endometrial carcinoma: prognostic factors and risk classification in 170 patients. Int J Radiat Oncol Biol Phys 53: 862-867, 2002.,Blake P, Lodge N, A Hern RP. An audit of outcome of adjuvant post-operative radiotherapy for 52 women with stage II carcinoma of the endometrium. Br J Radiol 73: 987-993, 2000.,Creasman WT, Morrow CP, Bundy BN, et al. Surgical pathologic spread patterns of endometrial cancer. A Gynecologic Oncology Group Study. Cancer 60 (8 Suppl): 2035-2041, 1987.,Chan JK, Wu H, Cheung MK, et al. The outcomes of 27,063 women with unstaged endometrioid uterine cancer. Gynecol Oncol 106: 282-288, 2007.,Lutman CV, Havrilesky LJ, Cragun JM, et al. Pelvic lymph node count is an important prognostic variable for FIGO stage I and II endometrial carcinoma with high-risk histology. Gynecol Oncol. 102: 92-97, 2006.,Cozad SC. Stage II adenocarcinoma of the endometrium: adjuvant radiotherapy and recurrence patterns. Int J Radiat Oncol Biol Phys 71: 205-212, 2008.
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