Evaluation of pediatric prostatic and retroperitoneal embryonal rhabdomyosarcoma with high Ki-67-case series study

Abstract

Embryonal rhabdomyosarcoma (ERMS) is a highly aggressive pediatric malignancy that can develop in various anatomical locations. This case series presents four pediatric patients diagnosed with ERMS, including one with the uncommon presentation of prostatic rhabdomyosarcoma. By analyzing clinical features, treatment strategies, and outcomes, this study aims to provide insights into the challenges of managing this malignancy in different anatomical sites. © 2025 Elsevier B.V., All rights reserved.