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Hipogonadotropik hipogonadizm hastalarında ciddi ovaryan hiperstimülasyon sendromu ve gonadotropin releasing hormon agonistiyle trigger: İki olgu sunumu

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dc.contributor.authorFunda Gode
dc.contributor.authorAli Sami Gurbuz
dc.contributor.authorFatma Kılıç
dc.contributor.authorRüya DEVEER
dc.contributor.authorZeynep Gurbuz
dc.contributor.institutionBAHÇEŞEHİR ÜNİVERSİTESİ
dc.contributor.institutionTanımlanmamış Kurum
dc.contributor.institutionNECMETTİN ERBAKAN ÜNİVERSİTESİ
dc.contributor.institutionMUĞLA SITKI KOÇMAN ÜNİVERSİTESİ
dc.contributor.institutionKOÇ ÜNİVERSİTESİ
dc.date.accessioned2025-09-20T19:58:37Z
dc.date.issued2020
dc.date.submitted20.01.2022
dc.description.abstractOver Hiperstimülasyon sendromu (OHSS) hipogonadotropik hipogonadizm hastalarında nadirdir. Burada ciddi OHSS olgusu ve gonadotropin salgılatıcı hormon (GnRH) agonist triggeriyle OHSS engellenmiş hipogonadotropik hipogonadizmi olan iki hasta sunulmuştur. İlk olgu 31 yaşında bir hastaydı. Üç kez in vitro fertilizasyon (IVF) tedavisi uygulanmış ancak olguda over hiperstimülasyon sendromu hiç gelişmemiş. Taze embriyo transferinden sonraki dokuzuncu günde şiddetli OHSS tanısı konuldu. Hastanede 66 gün kaldı ve batından 50,5 litre asit sıvısı aspire edildi. İkinci olgu 26 yaşında ve primer infertil hastaydı. Hiç IVF tedavisi görmemişti. IVF tedavisinden önce GnRH agonist stimülasyon testi uygulandı. Ovaryan stimülasyondan sonra GnRH agonist triggeri yapıldı. Toplanan 32 oosite rağmen OHSS meydana gelmemiştir. Hipogonadotropik hipogonadizm hastalarında şiddetli OHSS nadir olmakla birlikte gelişebilir. Eğer hipogonadotropik hipogonadizm hastalarında ovülasyon indüksiyonundan önce GnRH stimülasyon testi yapılırsa, hCG yerine GnRH agonist trigger yapılabilir ve OHSS önlenebilir.
dc.identifier.doi10.4274/tjod.galenos.2020.65031
dc.identifier.endpage93
dc.identifier.issn2149-9322
dc.identifier.issn2149-9330
dc.identifier.issue4
dc.identifier.startpage90
dc.identifier.urihttps://hdl.handle.net/20.500.14719/5031
dc.identifier.volume17
dc.language.isoen
dc.relation.journalTurkish Journal of Obstetrics and Gynecology
dc.subjectKadın Hastalıkları ve Doğum
dc.titleHipogonadotropik hipogonadizm hastalarında ciddi ovaryan hiperstimülasyon sendromu ve gonadotropin releasing hormon agonistiyle trigger: İki olgu sunumu
dc.typeResearch Article
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